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Bullous Pemphigoid in an Elderly Patient with Myelodysplastic Syndrome and Refractory Anemia Coupled with Excess of Blast

Lee YY, Bee PC, Lee CK, Naiker M, Ismail R

Bullous pemphigoid (BP) has a recognized association with solid organ tumors, but is relatively rare in hematological malignancies. We report a 67-year-old male who developed BP after being diagnosed with...
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Acquired Idiopathic Sideroblastic Anemia: A clinical study of 15 patients

Shin DG, Choi JY, Chang SK, Lee SC, Bae JD, Sohn SK, Lee KB, Whang KS

  • KMID: 2038490
  • Korean J Hematol.
  • 1997 Nov;32(3):360-366.
BACKGROUND: Acquired idiopathic sideroblastic anemia (AISA) is a heterogeneous condition. Most instances, involving only the erythroid line, are benign disease with a longer survival and a low propensity for evolution...
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A Clinical Study on Myelodysplastic Syndrome in Childhood

Park JE, Seo JJ, Moon HN, Park CJ, Chi HS, Ghim T

  • KMID: 2278180
  • Korean J Pediatr Hematol Oncol.
  • 1999 Oct;6(2):250-258.
PURPOSE: This study was undertaken to investigate the clinical characteristics and prognostic predictors of myelodysplastic syndrome (MDS) in childhood. Method: The characteristics and laboratory findings of 20 patients seen at...
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Identification of genes underlying different methylation profiles in refractory anemia with excess blast and refractory cytopenia with multilineage dysplasia in myelodysplastic syndrome

Lee S, Kwon HC, Kim SH, Oh SY, Lee JH, Lee YS, Seo D, Han JY, Kim HJ

BACKGROUND: Myelodysplastic syndrome (MDS) is a preleukemic condition that transforms into acute myeloid leukemia. However, the genetic events underlying this transformation remain poorly understood. Aberrant DNA methylation may play a...
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Hematologic Findings of Childhood Myelodysplastic Syndrome

Choi SJ, Park CJ, Seo EZ, Chi HS, Seo JJ, Ghim T, Moon HN

  • KMID: 1537187
  • Korean J Hematol.
  • 2000 Feb;35(1):21-26.
BACKGROUND: The myelodysplastic syndromes (MDS) in childhood is considered to be very rare and the nature of this disease in childhood is very different from that in adults. We analyzed...
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Effects of Low-Dose Cytosine Arabinoside Plus Granulocyte-Macrophage Colony-Stimulating Factor and the Changes of Peripheral Blood Lymphocytes and Bone Marrow Clonogenic Assay in Myelodysplastic Syndrome

Ko YW, Lee ST, Chong SY, Min YH, Hahn JS

  • KMID: 2083375
  • Korean J Hematol.
  • 1999 May;34(2):263-271.
BACKGROUND: In vitro data indicate that granulocyte-macrophage colony-stimulating factor (GM-CSF) induces leukemic clonogenic cells to proliferate, thereby enhancing preferentially the cytotoxicity of the cell cycle-specific drug cytosine arabinoside (Ara-C) when...
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A clinical study of myelodysplastic syndrome in children

Hah SH, Ahn HS

  • KMID: 1690506
  • J Korean Pediatr Soc.
  • 1993 Apr;36(4):556-567.
Myelodysplastic syndrome is a heterogeneous disease complex which is basically a clonal disorder and has characteristics of cytopenia of one or more cell series in peripheral blood and of dyspoiesis...
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Evaluation of Clinical Characteristics and Prognostic Factors in the Patients of Myelodysplastic Syndrome

Kim JH, Lee KH, Hyun MS

  • KMID: 2038494
  • Korean J Hematol.
  • 1997 Nov;32(3):398-408.
BACKGROUND: Myelodysplastic syndrome (MDS) is a disorder of the hematopoietic pluripotent stem cell. The treatment modality and its prognosis were based on the FAB classification. But, because there is a...
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Measurement of Serum sIL-2R, sCD8 and TNF-alpha Levels in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia

Lee BW, Do JH, Seo DY, Lee EY, Kim SH

  • KMID: 2039313
  • Korean J Clin Pathol.
  • 1997 Feb;17(1):10-20.
BACKGROUND: Soluble IL-2R, soluble CD8 and TNF-alpha are elevated in sera of some patients with hematological malignancies, and a marked elevation of these cytokines could be used to assess disease...
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Short-term Results of Hematopoietic Stem Cell Transplantation for Children with Myelodysplastic Syndrome

Lee J, Kim SY, Cho B, Jang PS, Chung NG, Kim HK

  • KMID: 2335602
  • J Korean Pediatr Soc.
  • 2002 Mar;45(3):370-375.
PURPOSE: In most cases, myelodysplastic syndrome(MDS) transforms into a more aggressive state or acute myelogenous leukemia; it's prognosis is very poor. It is believed that hematopoietic stem cell transplantation(HSCT) is...
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Correlation between Peripheral Blood Indices and Bone Marrow Dysplasia in Myelodysplastic Syndromes

Moon Y, Kim Y, Han K, Shim SI, Kim W

  • KMID: 2300496
  • Korean J Clin Pathol.
  • 1999 Feb;19(1):1-7.
BACKGROUND: Several studies about myelodysplastic syndromes (MDS) have demonstrated that patients with high score of erythrocytic and total dysplasia showed a significantly lower degree of acute myeloid leukemia (AML) development....
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Clinical Characteristics and Therapeutic Efficacy of Low Dose Cytarabine in High Risk Myelodysplastic Syndrome

Hyun DW, Kim DH, Jeong JT, Lee YH, Kim JK, Bae SG, Sohn SK, Lee KB, Shin DK, Hwang KS

  • KMID: 1532659
  • Korean J Hematol.
  • 1998 May;33(1):94-103.
BACKGROUND: High risk myelodysplastic syndrome has various clinical courses and refractoriness to various therapies. It is important to analyze clinical characteristics and therapeutic responses in high risk myelodysplastic syndrome. METHODS:...
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Comparison of FAB and WHO Classifications and Validation of WHO Classifications in 218 Korean Patients with Myelodysplastic Syndrome

Sohn YH, Park CJ, Seo EJ, Lee JH, Lee JH, Lee KH, Lee JS, Chi HS

  • KMID: 2305445
  • Korean J Lab Med.
  • 2003 Apr;23(2):71-77.
BACKGROUND: World Health Organization (WHO) proposed a new classification of myelodysplastic syndrome (MDS) in 1999, based on significant modifications of the original FAB proposals. The aim of the present study...
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A Clinical Observation of Childhood Myelodysplastic Syndrome

Park SY, Whang PG, Lee SY

  • KMID: 2072457
  • Korean J Pediatr Hematol Oncol.
  • 1997 Apr;4(1):78-89.
BACKGROUND: Childhood myelodysplastic syndrome(MDS) is a heterogenous disease complex which has characteristics of cytopenia in one or more hemopoietic cell lines in peripheral blood and of dysmorphisms of hemopoietic precursors...
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Clinical Implication of Serum Anti-p53 Antibodies and Overexpression of p53 Protein in Myelodysplastic Syndrome and Acute Myeloid Leukemia

Park JS, Park TH, Park TS, Jeong JS, Lim YT, Lee EY, Cho GJ

  • KMID: 2083422
  • Korean J Hematol.
  • 2001 Feb;36(1):1-8.
BACKGROUND: Alteration of p53 genes is rare, but it is related with progressive diseases in hematologic malignancies. The wild type of p53 protein is not usually detected, but mutated...
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Allogeneic Bone Marrow Transplantation for Myelodysplastic Syndromes

Kim JA, Kim DW, Kim YJ, Jang SW, Min CK, Park SK, Choi JH, Yoo JH, Lee JW, Han CW, Choi IB, Sin WS, Min WS, Kim WI, Kim DJ, Kim CC

  • KMID: 1534085
  • Korean J Hematol.
  • 1999 Feb;34(1):8-17.
BACKGROUND: The myelodysplastic syndromes (MDS) can be categorized as a group of clonal hematopoietic disorders characterized by ineffective hematopoiesis and peripheral cytopenias. Although the natural history of MDS varies, traditional...
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Clinical characteristics and prognosis according to the classification of myelodysplastic syndrome

Lee HW, Kim HI, Choi JM, Kang SY, Jang JH, Park JS, Choi JH, Lim HY, Kim HC

  • KMID: 2252396
  • Korean J Med.
  • 2006 Mar;70(3):253-260.
BACKGROUND: Myelodysplastic syndromes (MDS) are clonal hematologic stem cell disorders characterized clinically and morphologically by ineffective hematopoiesis. A consensus-defined French-American-British (FAB) classification and International Prognostic Scoring System (IPSS) for predicting...
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