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Proapoptotic role of nuclear clusterin in brain

Kim N, Choi WS

Clusterin (CLU) is a multifunctional glycoprotein that has secretory and nuclear isoforms. The two isoforms are known to play opposite roles in cell survival/death. In this review, we summarize recent...
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Bilateral asymmetric supernumerary heads of biceps brachii

Lee SE, Jung C, Ahn KY, Nam KI

Anatomical variations of the biceps brachii have been described by various authors, but the occurrence of bilateral asymmetric supernumerary heads is rare and has not been reported. We found three...
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Vitamin D3 regulates cell viability in gastric cancer and cholangiocarcinoma

Baek S, Lee YS, Shim HE, Yoon S, Baek SY, Kim BS, Oh SO

A low serum level of vitamin D has been associated with an increased incidence of gastrointestinal tract cancers. However, the effects of vitamin D3 have not been investigated in gastric...
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Bilateral variations of the head of the digastric muscle in Korean: a case report

Kyung DS, Lee JH, Lee YP, Kim DK, Choi IJ

The digastric muscle, as the landmark in head and neck surgery, has two bellies, of which various variations have been reported. In the submental region of a 72-year-old Korean male...
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The high dosage of earthworm (Eisenia andrei) extract decreases cell proliferation and neuroblast differentiation in the mouse hippocampal dentate gyrus

Yan BC, Yoo KY, Park JH, Lee CH, Choi JH, Won MH

Earthworm extract has shown anticancer characteristics. In the present study, we examined the effect of chronic treatment with a high dose of earthworm (Eisenia andrei) extract (EE) on cell proliferation...
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Co-localization of activating transcription factor 3 and phosphorylated c-Jun in axotomized facial motoneurons

Park BG, Lee JS, Lee JY, Song DY, Jeong SW, Cho BP

Activating transcription factor 3 (ATF3) and c-Jun play key roles in either cell death or cell survival, depending on the cellular background. To evaluate the functional significance of ATF3/c-Jun in...
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Intra-renal slow cell-cycle cells contribute to the restoration of kidney tubules injured by ischemia/reperfusion

Kim J, Kim JI, Na YK, Park KM

Renal epithelial cells damaged by ischemia/reperfusion (I/R) can be restored by timely and appropriate treatment. Recent studies have reported that intra renal adult kidney stem cells contribute to the restoration...
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Modulation by the GABAB receptor siRNA of ethanol-mediated PKA-alpha, CaMKII, and p-CREB intracellular signaling in prenatal rat hippocampal neurons

Lee HY, Yang BC, Lee ES, Chung JI, Koh PO, Park MS, Kim MO

Fetal alcohol syndrome (FAS) is a developmental neuropathology resulting from in utero exposure to ethanol; many of ethanol's effects are likely to be mediated by the neurotransmitter gamma-aminobutyric acid (GABA)....
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Psammomys obesus, a particularly important animal model for the study of the human diabetic nephropathy

Scherzer P, Katalan S, Got G, Pizov G, Londono I, Gal-Moscovici A, Popovtzer , Ziv E, Bendayan M

The Psammomys obesus lives in natural desert habitat on low energy (LE) diet, however when maintained in laboratory conditions with high energy (HE) diet it exhibits pathological metabolic changes resembling...
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Resveratrol activates AMPK and suppresses LPS-induced NF-kappaB-dependent COX-2 activation in RAW 264.7 macrophage cells

Yi CO, Jeon BT, Shin HJ, Jeong EA, Chang KC, Lee JE, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS

AMP-activated protein kinase (AMPK), an enzyme involved in energy homeostasis, regulates inflammatory responses, but its precise mechanisms are not fully understood. Recent evidence has shown that resveratrol (RES), an AMPK...
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