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The effect of silica on the development of experimental Acanthamoeba meningoencephalitis with reference to the macrophage role in mice

Lee HS, Shin HJ, La MS, Im K

The role of macrophages was observed in intranasally infected C3H/HeJ mice with trophozoites (3 x 10(5)) of Acanthamoeba culbertsoni which was a kind of free-living amoebae inducing meningoencephalitis in human...
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Acanthamoeba Keratitis: Microscopic and Ultrastructural Findings: A case report

Lee HJ, Choi YJ, Hahn TW, Kang SJ, Kim BK, Shim SI

  • KMID: 2141057
  • Korean J Pathol.
  • 1998 Jun;32(6):466-469.
Acanthamoeba keratitis is uncommon and rarely reported in Korea. It has been reported in world literature as a very severe, progressive necrotizing stromal keratitis due to a non-parasitic free-living amoeba....
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Contamination of Acanthamoeba in Contact Lens Care System

Lee SM, Choi YJ, Chung DI

  • KMID: 2147740
  • J Korean Ophthalmol Soc.
  • 1997 May;38(5):756-761.
Recently, the number of reports of Acanthamoeba keratitis has been increased apparently as a consequence of association with use of contact lenses, contaminated contact lens care system and high concern...
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Adherence of Acanthamoeba Lugdunensis on the Corneal Epithelium in Organ Cultured Human Cornea: A Scanning and Transmission Electron Microscopy Study

Kim SM, Hahn TW

  • KMID: 2147614
  • J Korean Ophthalmol Soc.
  • 1999 May;40(5):1195-1201.
The purpose of this study was to investigate the ability of Acanthamoeba to adhere to the epithelial cells of human cornea. Human corneas, obtained through the eye bank of Catholic...
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Immunological approach for classification of free-living amoeba in Korea

Shin HJ, Kim CH, Im KI

Acanthamoeba spp., free-living amoebae inhabited in moist soil, pond, freshwater, sewage, atmosphere and swimming pool, may be causative protozoa of the fatal primary amoebic meningoencephalitis in experimental animals and humans....
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Nation-wide Survey for Acanthamoeba from Contact Lens Care Systems in Korea

Hahn TW, Chung DI, Kong HH, Han YH

  • KMID: 2205283
  • J Korean Ophthalmol Soc.
  • 1998 Apr;39(4):667-672.
In order to determine the contamination status of contact lens care system by Acanthamoeba, a nation-wide survey was carried out for the detection of amoeba from the storage cases and...
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Upregulated expression of the cDNA fragment possibly related to the virulence of Acanthamoeba culbertsoni

Im KI, Park KM, Yong TS, Hong YP, Kim TE

Identification of the genes responsible for the recovery of virulence in brain-passaged Acanthamoeba culbertsoni was attempted via mRNA differential display-polymerase chain reaction (mRNA DD-PCR) analysis. In order to identify...
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Natural killer cell activity in mice infected with free-living amoeba with reference to their pathogenicity

Kim KH, Shin CO, Im K

The purpose of this observation was to investigate the natural killer cell activities in mice infected with pathogenic free-living amoeba, Naegleria fowleri and Acanthamoeba culbertsoni according to the infection doses,...
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Cytopathic Change and Inflammatory Response of Human Corneal Epithelial Cells Induced by Acanthamoeba castellanii Trophozoites and Cysts

Sohn HJ, Seo GE, Lee JH, Ham AJ, Oh YH, Kang H, Shin HJ

Acanthamoeba castellanii has ubiquitous distribution and causes primary acanthamoebic keratitis (AK). AK is a common disease in contact lens wearers and results in permanent visual impairment or blindness. In this...
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Amoebic PI3K and PKC Is Required for Jurkat T Cell Death Induced by Entamoeba histolytica

Lee YA, Kim KA, Min A, Shin MH

The enteric protozoan parasite Entamoeba histolytica is the causative agent of human amebiasis. During infection, adherence of E. histolytica through Gal/GalNAc lectin on the surface of the amoeba can induce...
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Natural occurrence of Mycobacterium as an endosymbiont of Acanthamoeba isolated from a contact lens storage case

Yu HS, Jeong HJ, Hong YC, Seol SY, Chung DI, Kong HH

Recent in vitro studies have revealed that a certain Mycobacterium can survive and multiply within freeliving amoebae. It is believed that protozoans function as host cells for the intracellular replication...
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Isolation and Genotyping of Acanthamoeba spp. as Neglected Parasites in North of Iran

Shokri A, Sarvi S, Daryani A, Sharif M

Acanthamoeba, a free-living amoeba, is widely distributed in the environment, water sources, soil, dust, and air. It can cause keratitis in contact lens wearers with poor hygiene and also fatal...
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A Case of Steroid Treated Amebic Colitis Misdiagnosed as Eosinophilic Colitis

Cheong ES, Jo YJ, An SB, Kim SH, Park YS, Lee WM, Hong YO

  • KMID: 1442183
  • Korean J Gastrointest Endosc.
  • 2011 Jul;43(1):42-46.
Some cases have reported that amebic colitis leads to serious complications that are caused by a misdiagnosis of an inflammatory bowel disease and consequential ill-managed steroid therapy. Therefore, it should...
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The role of domestic tap water in Acanthamoeba contamination in contact lens storage cases in Korea

Jeong HJ, Yu HS

A survey was carried out from August to December 2004 in Pusan, Korea to document the presence of free-living amoeba (FLA), including the genus Acanthamoeba, in both contact lens storage...
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Ultrastructural changes of Acanthamoeba cyst of clinical isolates after treatment with minimal cysticidal concentration of polyhexamethylene biguanide

Kong HH, Chung DI

In order to understand the action mechanism of polyhexamethylene biguanide (PHMB) to the cyst of Acanthamoeba on the morphological basis, the cysts of four corneal isolates of Acanthamoeba were treated...
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Immunological tests by anti-free-living amoebas serum produced in experimental animals I. Immobilization of free-living amoebas in vitro by rabbit antiserum

Im KI, Oh HS

Rabbits were immunized with free-living amoebas by intravenous injections. The amoebas were Acanthamoeba culbertsoni and Naegleria fowleri and obtained by axenic cultivation in CGVS medium. Each rabbit received 10(6) of...
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Down-Regulation of Cellulose Synthase Inhibits the Formation of Endocysts in Acanthamoeba

Moon EK, Hong Y, Chung DI, Goo YK, Kong HH

  • KMID: 1792159
  • Korean J Parasitol.
  • 2014 Apr;52(2):131-135.
Acanthamoeba cysts are resistant to unfavorable physiological conditions and various disinfectants. Acanthamoeba cysts have 2 walls containing various sugar moieties, and in particular, one third of the inner wall is...
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Primary Amebic Meningoencephalitis: A Case Report

Chen M, Ruan W, Zhang L, Hu B, Yang X

Primary amebic encephalitis (PAM) is a devastating central nervous system infection caused by Naegleria fowleri, a free-living amoeba, which can survive in soil and warm fresh water. Here, a 43-year-old...
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Ultrastructural observation of human neutrophils during apoptotic cell death triggered by Entamoeba histolytica

Sim S, Kim KA, Yong TS, Park SJ, Im KI, Shin MH

Neutrophils are important effector cells against protozoan extracellular parasite Entamoeba histolytica, which causes amoebic colitis and liver abscess in human beings. Apoptotic cell death of neutrophils is an important event...
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Interaction of Escherichia coli K1 and K5 with Acanthamoeba castellanii Trophozoites and Cysts

Matin A, Jung SY

The existence of symbiotic relationships between Acanthamoeba and a variety of bacteria is well-documented. However, the ability of Acanthamoeba interacting with host bacterial pathogens has gained particular attention. Here, to...
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