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Serum vitamin D levels and ovarian reserve markers in secondary amenorrhea patients: Is there a link?

Kim GM, Jeon GH

Objective To investigate whether serum 25-hydroxyvitamin D [25(OH)D] level is associated with ovarian reserve markers in secondary amenorrhea (SA) patients. Methods Sixty-three women diagnosed with SA were recruited during 12 months...
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Evaluation and management of amenorrhea related to congenital sex hormonal disorders

Yoon JY, Cheon CK

Primary amenorrhea is a symptom with a substantial list of underlying etiologies which presents in adolescence, although some conditions are diagnosed in childhood. Primary amenorrhea is defined as not having...
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Pituitary magnetic resonance imaging abnormalities in young female patients with hypogonadotropic hypogonadism

Kang JY, Kim SH, Kim H, Ki H, Lee MH

OBJECTIVE: To elucidate the association between clinical and laboratory characteristics and pituitary magnetic resonance imaging (MRI) abnormalities in young female patients with hypogonadotropic hypogonadism (HH). METHODS: We retrospectively investigated a series...
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Amenorrhea and Menopause in Patients with Breast Cancer after Chemotherapy

Shin JJ, Choi YM, Jun JK, Lee KH, Kim TY, Han W, Im SA

PURPOSE: The probability of ovarian failure after cytotoxic chemotherapy in patients with breast cancer has not been well established in Korea. This study aimed to assess the rate of ovarian...
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Amenorrhea as a Side Effect of Low Dose Aripiprazole: An Adolescent Case

Guler G, Kutuk MO, Kara H

Amenorrhea, oligomenorrhea, galactorrhoea, gynecomastia, infertility, and sexual dysfunction may arise as a consequence of hyperprolactinemia. Hyperprolactinemia is one of major side effects of treatment with antipsychotics, but aripiprazole is known...
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Feature of amenorrhea in postoperative tamoxifen users with breast cancer

Kim H, Han W, Ku SY, Suh CS, Kim SH, Choi YM

OBJECTIVE: Tamoxifen has been used to prevent the recurrence of breast cancer. However, tamoxifen-users frequently experience amenorrhea and it can be confused from that caused by other hormonal abnormalities. In...
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Escitalopram-Induced Amenorrhea and False Positive Urine Pregnancy Test

Selvaraj V, Hour S, Gunasekar , Gray C, Smith JF

Escitalopram is a selective serotonin reuptake inhibitor antidepressant approved by the Food and Drug Administration for the treatment of major depressive disorder and generalized anxiety disorder. A 34-year-old female patient...
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A case of 17 alpha-hydroxylase deficiency

Kim SM, Rhee JH

17alpha-hydroxylase and 17,20-lyase are enzymes encoded by the CYP17A1 gene and are required for the synthesis of sex steroids and cortisol. In 17alpha-hydroxylase deficiency, there are low blood levels of...
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Ovarian Ablation Using Goserelin Improves Survival of Premenopausal Patients with Stage II/III Hormone Receptor-Positive Breast Cancer without Chemotherapy-Induced Amenorrhea

Zhou J, Wu SG, Wang JJ, Sun JY, Li FY, Lin Q, Lin HX, He ZY

PURPOSE: The purpose of this study was to assess the value of ovarian ablation using goserelin in premenopausal patients with stage II/III hormone receptor-positive breast cancer without chemotherapy-induced amenorrhea (CIA). MATERIALS...
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Causes of amenorrhea in Korea: Experience of a single large center

Kwon SK, Chae HD, Lee KH, Kim SH, Kim CH, Kang BM

OBJECTIVE: To investigate the causes of amenorrhea in Korean women. METHODS: Medical records from 1,212 women with amenorrhea who visited the Department of Obstetrics and Gynecology, Asan Medical Center, between January...
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Magnetic Resonance Evaluation of Mullerian Remnants in Mayer-Rokitansky-Kuster-Hauser Syndrome

Yoo RE, Cho JY, Kim SY, Kim SH

OBJECTIVE: To analyze magnetic resonance imaging (MRI) findings of Mullerian remnants in young females clinically suspected of Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome in a primary amenorrhea workup. MATERIALS AND METHODS: Fifteen young females...
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Metformin for Treatment of Antipsychotic-Induced Amenorrhea in Female Schizophrenic Patients: Report of Two Cases

Woo YS, Bahk WM

  • KMID: 2287452
  • Korean J Psychopharmacol.
  • 2013 Oct;24(4):186-189.
Amenorrhea is a common adverse event in female patients treated with antipsychotics. Because amenorrhea can produce difficulties for women suffering from schizophrenia, attempts should be made to alleviate antipsychotic-induced amenorrhea....
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Leptin as a Modulator of Neuroendocrine Function in Humans

Khan SM, Hamnvik OP, Brinkoetter M, Mantzoros

Leptin, a peptide hormone secreted by adipocytes in proportion of the amount of energy stored in fat, plays a central role in regulating human energy homeostasis. In addition, leptin plays...
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A Case of Extreme Uterine Hypotrophy in Hypogonadotropic Hypogonadism with Partial GH Deficiency

Min SR, Choo YK, Cho HS, Lee HS, Kim JK, Lee HA, Ahn SY

Congenital hypogonadotropic hypogonadism is one of the causes of pubertal failure and primary amenorrhea, it is related to uterine hypotrophy. If the uterus is extremely hypotrophied, it is difficult to...
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A case of resistant ovary syndrome

Kim SS, Jo IH, Jeong EJ, Seo YJ, Byun JM, Jeong DH, Sung MS, Kim KT, Lee KB

A 21-year-old female with primary amenorrhea, sexual infantilism, and phenotypic female visited our Obstetrics and Gynecology Clinics. The patient showed elevated follicle stimulating hormone and luteinizing hormone, decreased estradiol, normal...
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A case of Rathke's cleft cyst presenting with amenorrhea

Park YS, Lee MH, Kim TH, Jang HY, Lee GM

A 28-year-old female presented with Rathke's cleft cysts (RCC) manifesting as primary amenorrhea and no development of secondary sexual characteristics. She had no symptoms of headache, visual disturbance, anosmia or...
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A Case of Mayer-Rokitansky-Kuster-Hauser (MRKH) Syndrome with Bilateral Gonadal Agenesis

Kim BG, Lee CW, Kim SM, Jeon YK, Kim SS, Kim BH, Kim IJ, Choi YS

  • KMID: 2308557
  • Kosin Med J.
  • 2011 Jun;26(1):93-97.
Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is characterized by congenital aplasia of the uterus and the upper part of the vagina in women showing normal development of secondary sexual characteristics and a normal...
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A Case of Trisomy 8 Mosaicism in a Patient with Secondary Amnorreha without Abnormal Phenotype

Kang HS, Son YS, Kim SY, Park CM, Shim SS

Constitutional trisomy 8 mosaicism (CT8M) is a relatively rare aneuploidy in humans with characteristic phenotypes including typical craniofacial feature (such as deformed skull, prominent forehead, low-set and/or dysplastic ears), skeletal...
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Retrospective Multicenter Study on Clinical Aspects in Premature Ovarian Failure

Huh JS, Seo SK, Kim MR, Chung HW, Yoon BK, Lee BS, Kang BM, Choi H, Park HM, Kim JG, The Study Group of Menopause

OBJECTIVES: Premature ovarian failure (POF) is a syndrome defined as the cessation of ovarian function before the age of 40 years that is characterized by amenorrhoea associated with elevated gonadotropin...
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Effects of Antipsychotics-Induced Amenorrhea on Attitudes Toward Treatment and Quality of Life in Women with Schizophrenia

Kim MH, Kong BG, Jung DU, Kang JW, Moon JJ, Kim JE, Song TH, Shin HK, Lim JS, Shim JC

  • KMID: 2287483
  • Korean J Psychopharmacol.
  • 2011 Oct;22(4):199-207.
OBJECTIVE: This study was aimed to identify the correlation between antipsychotics-induced amenorrhea, and attitudes toward treatment and quality of life in women with schizophrenia. METHODS: Twenty female schizophrenic patients with antipsychotics-induced...
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