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Current Specific Immunotherapy for Allergic Rhinitis: Perspectives from Otorhinolaryngologists

Rhee CS

No abstract available.
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Cysteinyl Leukotrienes and Their Receptors; Emerging Concepts

Kanaoka Y, Boyce JA

Cysteinyl leukotrienes (cys-LTs) are potent mediators of inflammation derived from arachidonic acid through the 5-lipoxygenase/leukotriene C4 synthase pathway. The derivation of their chemical structures and identification of their pharmacologic properties...
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Predictive Value of the TRACK Questionnaire as a Measure of Asthma Control in Preschool Aged Children

Yilmaz O, Turkeli A, Sahin S, Yuksel H

Assessment of asthma control in preschool children is important for therapeutic decisions. Aim of this study was to evaluate the predictive value of TRACK questionnaire scores for subsequent clinical parameters...
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Gene - Gene Interactions Among MCP Genes Polymorphisms in Asthma

Lee JH, Park CS

PURPOSE: Monocyte chemoattractant proteins (MCPs) are important cytokines that involved in cellular activation and releasing of inflammatoy mediators by basophils and eosinophils in allergic disease. Some MCP gene variants implicate...
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Clinical Characteristics of Angioedema With Eosinophilia

Cho HJ, Yoo HS, Kim MA, Shin YS, Ye YM, Nahm DH, Kim JH, Choi JH, Park SY, Park HS

Angioedema with eosinophilia (AE) is a very rare allergy disease, case reports of which have been published sporadically since 1984. Here, we retrospectively analyzed the clinical features of 10 AE...
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Systemic Inflammation in Older Adults With Asthma-COPD Overlap Syndrome

Fu JJ, McDonald V, Gibson PG, Simpson JL

PURPOSE: The role of systemic inflammation on asthma-COPD overlap syndrome is unknown. This study aimed to examine systemic inflammation in asthma-COPD overlap syndrome, and to identify associations between clinical characteristics...
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Wheat - Dependent Exercise-Induced Anaphylaxis Occurred With a Delayed Onset of 10 to 24 hours After Wheat Ingestion: A Case Report

Rongfei Z, Wenjing L, Nan H, Guanghui L

Wheat-dependent exercise-induced anaphylaxis (WDEIA) usually occurs 1 to 4 hours after wheat ingestion and the pathophysiology of WDEIA remains unknown. It is recommended that WDEIA patients refrain from exercise for...
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Epidermal Permeability Barrier Defects and Barrier Repair Therapy in Atopic Dermatitis

Lee HJ, Lee SH

Atopic dermatitis (AD) is a multifactorial inflammatory skin disease perpetuated by gene-environmental interactions and which is characterized by genetic barrier defects and allergic inflammation. Recent studies demonstrate an important role...
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The Utility of Serum Tryptase in the Diagnosis of Food-Induced Anaphylaxis

Wongkaewpothong P, Pacharn P, Sripramong C, Boonchoo S, Piboonpocanun S, Visitsunthorn N, Vichyanond P, Jirapongsananuruk O

PURPOSE: This study investigates the utility of serum tryptase for the confirmation of shrimp-induced anaphylaxis. METHODS: Patients with a history of shrimp allergy and positive skin prick tests (SPT) to commercial...
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Identification of a Novel Mutation in the CYBB Gene, p.Asp378Gly, in a Patient With X-linked Chronic Granulomatous Disease

Song SM, Park MR, Kim DS, Kim J, Kim YJ, Ki CS, Ahn K

Chronic granulomatous disease (CGD) is a rare immunodeficiency disease, which is characterized by the lack of a functional nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in phagocytes. The disease presents leukocytosis,...
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Trends in Specific Immunotherapy for Allergic Rhinitis: A Survey of Chinese ENT Specialists

Zhou H, Tao QL, Wei JM, Xu G, Cheng L

PURPOSE: Specific immunotherapy (SIT) is a suitable but uncommon treatment option for allergic rhinitis (AR) in China. The current understanding and attitude of Chinese ENT (ear, nose, and throat) specialists...
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Influence of Chronic Sinusitis and Nasal Polyp on the Lower Airway of Subjects Without Lower Airway Diseases

Lee SY, Yoon SH, Song WJ, Lee SH, Kang HR, Kim SS, Cho SH

PURPOSE: Upper and lower respiratory tract pathologies are believed to be interrelated; however, the impact of upper airway inflammation on lung function in subjects without lung disease has not been...
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Perinatal Immunization With Vaccine-Grade Listeria monocytogenes Provides Protection Against Murine Th2 Airway Inflammation

Aloyouni S, Segeritz C, Sherrid AM, Gold MJ, Loeffler D, Blanchet M, Cai B, Hirota J, McNagny KM, Kollmann T

PURPOSE: Asthma is a chronic respiratory disorder that leads to inflammation and narrowing of the airways. Its global prevalence has attained epidemic levels and treatment options that reach beyond temporary...
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Specific B-cell Epitope of Per a 1: A Major Allergen of American Cockroach (Periplaneta americana) and Anatomical Localization

Sookrung N, Khetsuphan T, Chaisri U, Indrawattana N, Reamtong O, Chaicumpa , Tungtrongchitr A

PURPOSE: Cockroach (CR) is a common source of indoor allergens, and Per a 1 is a major American CR (Periplaneta americana) allergen; however, several attributes of this protein remain unknown....
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Maternal Genetic Variants of IL4/IL13 Pathway Genes on IgE With "Western or Eastern Environments/Lifestyles"

Zhang G, Khoo SK, Makela JM, Candelaria P, Hayden MC, von Hertzen L, Laatikainen T, Vartiainen E, Goldblatt , Haahtela T, LeSouef NP

PURPOSE: We investigated maternal genetic effects of four IL-4/IL-13 pathway genes as well as their interactions with the "Western or Eastern lifestyles/environments" on IgE in Karelian children. METHODS: This study included...
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