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Unraveling the Genetic Basis of Asthma and Allergic Diseases

Meng JF, Rosenwasser LJ

Asthma and allergic diseases are believed to be complex genetic diseases which may result from the interaction of multiple genetic factors and environmental stimuli. In past decades, great efforts have...
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Immunomodulators for Asthma

Dimov VV, Casale TB

New information regarding the molecular mechanisms of allergic disorders has led to a variety of novel therapeutic approaches. This article briefly reviews the pathogenesis of asthma and allergic diseases, discusses...
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Overlap Between Asthma and COPD: Where the Two Diseases Converge

Kim SR, Rhee YK

Asthma and chronic obstructive pulmonary disease (COPD) are traditionally recognized as distinct diseases, with some clearly separate characteristic. Asthma originates in childhood, is associated with allergies and eosinophils, and is...
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Effects of Smoking Cessation on Airflow Obstruction and Quality of Life in Asthmatic Smokers

Jang AS, Park SW, Kim DJ, Uh S, Kim YH, Whang HG, Lim GI, Park CS

PURPOSE: Smoking elicits airway inflammation and airflow obstruction in patients with asthma, even after smoking cessation. The aim of this study was to examine the effects of smoking cessation on...
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Physicians' Preferences for Asthma Guidelines Implementation

Kang MK, Kim BK, Kim TW, Kim SH, Kang HR, Park HW, Chang YS, Kim SS, Min KU, Kim YY, Cho SH

PURPOSE: Patient care based on asthma guidelines is cost-effective and leads to improved treatment outcomes. However, ineffective implementation strategies interfere with the use of these recommendations in clinical practice. This...
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Probable Role of Beta 2-Adrenergic Receptor Gene Haplotype in Toluene Diisocyanate-Induced Asthma

Ye YM, Kang YM, Kim SH, Lee HY, Kim CW, Park CS, Hong CS, Park HS

PURPOSE: A genetic polymorphism of the beta 2-adrenergic receptor is a major factor associated with the asthmatic phenotype. The association of this polymorphism with toluene diisocyanate (TDI)-induced asthma has not...
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A Case of Recurrent Toxocariasis Presenting With Urticaria

Kim MH, Jung JW, Kwon JW, Kim TW, Kim SH, Cho SH, Min KU, Kim YY, Chang YS

Human toxocariasis is the most prevalent helminthiasis in Korea and other industrialized countries. The clinical features of toxocariasis are diverse, according to the involved organ. Typically, Toxocara spp. infection is...
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A Role of Staphyococcus aureus, Interleukin-18, Nerve Growth Factor and Semaphorin 3A, an Axon Guidance Molecule, in Pathogenesis and Treatment of Atopic Dermatitis

Ikezawa Z, Komori J, Ikezawa Y, Inoue Y, Kirino M, Katsuyama , Aihara M

Staphylococcus aureus (SA) is usually present not only in the skin lesions of atopic dermatitis (AD) but also in the atopic dry skin. SA discharges various toxins and enzymes that...
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