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Phenotypes of allergic diseases in children and their application in clinical situations

Lee E, Hong SJ

Allergic diseases, including allergic rhinitis, asthma, and atopic dermatitis, are common heterogeneous diseases that encompass diverse phenotypes and different pathogeneses. Phenotype studies of allergic diseases can facilitate the identification of...
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Epidemiology of allergic diseases in Korean children

Lee E, Lee SY, Yang HJ, Hong SJ

In order to overcome a certain disease, it is necessary to confirm the prevalence, natural course and risk factors of the disease. The Korean Academy of Pediatric Allergy and Respiratory...
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Time trends of the prevalence of allergic diseases in Korea: A systematic literature review

Kang SY, Song WJ, Cho SH, Chang YS

The prevalence of allergic diseases has increased dramatically in recent decades, and are now considered major chronic diseases at the global level. The increasing burden of allergic diseases has led...
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Clostridium difficile colonization and/or infection during infancy and the risk of childhood allergic diseases

Lee SH, Gong YN, Ryoo E

PURPOSE: The gut microbiota can influence several diseases through immune modulation; however, the exact role of microbes such as Clostridium difficileand the relationship between microbiota colonization and allergic diseases are...
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Prenatal Maternal Distress and Allergic Diseases in Offspring: Review of Evidence and Possible Pathways

Suh DI, Chang HY, Lee E, Yang SI, Hong SJ

Recent studies have suggested a close association between prenatal maternal distress and allergic diseases in the offspring. We selected relevant birth-cohort or national registry studies using a keyword search of...
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Prenatal Exposure to Drugs and Allergic Diseases in Offspring

Lee HC

Recent studies reported increased risks for the development of allergic diseases in children after prenatal exposure to drugs. The mechanisms by which drug exposure may actually cause allergic diseases are...
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Making allergic and hypersensitivity conditions visible in the International Classification of Diseases-11

Tanno LK, Calderon M, Demoly P

Understanding that the International Classification of Diseases (ICD)-11 revision would be an opportunity to standardize the code definitions for all allergic and hypersensitivity conditions, an international collaboration of Allergy Academies,...
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The Importance of Allergen Avoidance in High Risk Infants and Sensitized Patients: A Meta-analysis Study

Huiyan W, Yuhe G, Juan W, Junyan Z, Shan W, Xiaojun Z, Ailin T

PURPOSE: At this time, there is uncertainty regarding whether allergen avoidance is the most appropriate strategy for managing or preventing allergies. The purpose of this study was to evaluate the...
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Frequently asked questions in allergy practice

Tan XX, Xie P, Kwek JL, Kwek SY, Yang Z, Soon W, Leong JL, Wang DY

BACKGROUND: Over the last 10-20 years, international guidelines and consensus statements for the management of common allergic diseases (e.g. allergic rhinitis and asthma) have been developed and disseminated worldwide. However,...
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Association between exposure to antimicrobial household products and allergic symptoms

Hong S, Kwon HJ, Choi WJ, Lim WR, Kim J, Kim K

OBJECTIVES: Antimicrobial chemicals are used in a variety of household and personal care products. Exposure to antimicrobial household products has been hypothesized to lead to allergic diseases in children. METHODS: We...
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Epigenetics in Allergic Diseases

Jang AS

The epigenetics is the study of changes in gene expression or celluar phenotype caused by mechanisms other than changes in the underlying DNA sequence. Epigenetic regulation in asthma and allergic...
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Relationship between serum total IgE, specific IgE, and peripheral blood eosinophil count according to specific allergic diseases

Koh HS, Lee KS, Han DH, Rha YH, Choi SH

PURPOSE: Elevated IgE, and blood eosinophil count are considered the hallmarks of allergic diseases, while the levels of those parameters are shared with normal population. This study is aimed to...
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Suppressive effects of Schizandra chinensis Baillon water extract on allergy-related cytokine generation and degranulation in IgE-antigen complex-stimulated RBL-2H3 cells

Chung MJ, Kim JM, Lee S, Kim T, Kim D, Baek J, Kim T, Lee J, Kim K, Yoon JA, Choe M

  • KMID: 2313580
  • Nutr Res Pract.
  • 2012 Apr;6(2):97-105.
Schizandra chinensis Baillon is a traditional folk medicine plant that is used to treat and prevent several inflammatory diseases and cancer in Korea, but the underlying mechanisms involved in its...
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The Prevalence of Atopic Dermatitis, Asthma, and Allergic Rhinitis and the Comorbidity of Allergic Diseases in Children

Hong S, Son DK, Lim WR, Kim SH, Kim H, Yum HY, Kwon H

  • KMID: 2380173
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012006.
OBJECTIVES: Childhood allergic diseases are a major concern because they lead to a heavy economic burden and poor quality of life. The purpose of this study was to investigate the...
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Climate change and respiratory allergic diseases

Kim SH, Yoon HJ

There is a firm consensus that Earth's climate has been changed and will be changed in further future due to increasing greenhouse gas emissions. Climate change affects human health and...
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Unraveling the Genetic Basis of Asthma and Allergic Diseases

Meng JF, Rosenwasser LJ

Asthma and allergic diseases are believed to be complex genetic diseases which may result from the interaction of multiple genetic factors and environmental stimuli. In past decades, great efforts have...
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The Relation of Overweight to Asthma and Other Allergic Diseases in High School Students in Korea

Shin NE, Yoo SM, Kim KN, Lee SY, Lee EJ, Kim HB, Kim BS, Hong SJ, Kim JH, Lee SY

BACKGROUND: The worldwide prevalence of obesity and allergic diseases has increased. We aimed to explore the relation of overweight to asthma, atopic dermatitis, allergic rhinitis and conjunctivitis in a sample...
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Association of Breast-feeding and Allergic Diseases in Preschool Aged Children

Shin JW, Kim WK, Yoon HS

  • KMID: 2314999
  • Pediatr Allergy Respir Dis.
  • 2009 Dec;19(4):374-382.
PURPOSE: The effect of breastfeeding on the development of allergic disease has been assessed in many studies but remains controversial. Thus, we evaluated the prevalence of allergic disease and its...
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CpG DNA for Treatment of Allergic Diseases

Choi SM

  • KMID: 1979722
  • Korean J Pediatr.
  • 2005 Mar;48(3):251-259.
Atopy is a highly prevalent and serious health problem. The prevalence and severity of asthma and allergic diseases have increased over recent decades, particularly in industrialized nations. Early life infections...
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Comparison of Plain X-rays and OMU (Osteo-Meatal-Unit) CT Scans in Children with Chronic Sinusitis

Ryu HJ, Lee GW, Kim IK, Seong H, Choi CH, Jung ST

  • KMID: 2314187
  • Pediatr Allergy Respir Dis.
  • 1998 Sep;8(2):273-279.
PURPOSE: In general, sinusitis in children is diagnosed by clinical symptom and paranasal sinus x-ray. Sinus plain x-rays in children is simple, inexpensive, and speedy. However, it requires proper interpretative...
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