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Changes in allergen sensitization in children with allergic diseases in the 1980 to 2019

Jung JH, Kim GE, Park M, Kim SY, Kim MJ, Lee YJ, Kim YH, Kim KW, Sohn MH

Purpose: Allergen sensitization is constantly changing, and understanding these changes can help manage and prevent allergic diseases. This research analyzed and compared the changes in allergen sensitization in children diagnosed...
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Analysis of Positive Rates for Standard Allergens of Patch Test in Korea with Literature Review

Kwon B, Lee MY, Byun JY, Choi YW, Choi HY

  • KMID: 2504342
  • Korean J Dermatol.
  • 2020 Jul;58(6):371-381.
Background: Korean standard series (KSS) have not changed for 20 years. Moreover, the Korea Food and Drug Administration has suspended import licensing of Cosmetic series (ChemotechniqueⓇ). Objective: To analyze trends...
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Inhibition of Cross-Reactive Carbohydrate Determinant–Specific IgEs Reduce False Positive Reponses to Multiple Allergen Simultaneous Test–Immunoblot Assay: A Case Study

Song DY, Lee JH, Kim SM, Jun SH, Lee K, Song SH, Song J

Cross-reactive carbohydrate determinants (CCDs) are simple carbohydrates linked to amino acid chains; they are found in pollens, vegetable foods, insect, and Hymenoptera venoms and are broadly cross-reactive with CCD-specific IgE...
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Validation of a Multiplex Assay for Measuring Specific IgG4

Kim SR, Park KH, Lee JE, Kim BJ, Lim KJ, Park JW

Purpose: Specific IgG4 (sIgG4) increases with allergen specific immunotherapy and may reflect a state of immune tolerance in food allergy. While ImmunoCAP® has been widely used to measure sIgG4 to...
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Atopic Patients Who Fulfilled Rome III Criteria for Irritable Bowel Syndrome Had Higher Animal Danders Sensitization

Siah KTH, Santosa A, Cheung CKY, Soh AYS, Bigliardi

  • KMID: 2500684
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):267-273.
  • doi: 10.5056/jnm19181
Background/Aims The relationship between animal exposure and irritable bowel syndrome (IBS) is debated. Epidemiological studies have shown that atopy is more prevalent in IBS patients and vice versa. We set...
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Utilization of Component-Resolved Diagnosis in Precision Allergology

Lee JH

It is very important to identify the causal allergen of each patient in the diagnosis and treatment of allergic diseases. An experimental method of specific IgE testing for single clinically...
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Bronchial Response to High and Low Molecular Weight Occupational Inhalant Allergens

Lipińska-Ojrzanowska A, Nowakowska-Świrta E, Wiszniewska M, Walusiak-Skorupa J

PURPOSE: Occupational asthma may be induced by high- or low-molecular weight allergens (HMWA or LMWA, respectively). The study was conducted to compare the pattern of bronchial response in 200 HMWA-induced...
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Efficacy of Allergen Immunotherapy for Allergic Asthma in Real World Practice

Rhyou HI, Nam YH

PURPOSE: Allergen immunotherapy (AIT) induces immunological tolerance, and there is increasing evidence of the clinical efficacy of AIT in the treatment of allergic asthma. However, the optimal parameters for asthma...
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Association of Sensitization to Different Aeroallergens With Airway Function and Nasal Patency in Urban Children

Lee S, Koh HY, Yon DK, Lee SW, Ha EK, Sung M, Lee KS, Jee HM, Sheen YH, Han MY

PURPOSE: Children with sensitization to aeroallergens have decreased lung function and nasal patency. Our purpose was to determine the association of sensitization to different aeroallergens with airway function and nasal...
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Validation of PROTIA™ Allergy-Q 64 Atopy® as a Specific IgE Measurement Assay for 10 Major Allergen Components

Kim SR, Park KH, Lee JH, Kim BJ, Hwang JH, Lim KJ, Park JW

PURPOSE: Component-resolved diagnostics (CRD) is expected to provide additional diagnostic information in allergic patients. PROTIA™ Allergy-Q 64 Atopy®, a recently developed CRD-based multiplex specific immunoglobulin E (sIgE) assay, can quantitatively...
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Indoor pet ownership in infancy is a risk factor for the development of sensitization to pets and asthma in childhood

Jung S, Noh SR, Lee SY, Yoon J, Cho HJ, Kim YH, Suh DI, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Lee E, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Hong SJ

PURPOSE: It is controversial whether indoor pet exposure is either a risk or protective factor developing sensitization to pet allergens or asthma. Therefore, we investigated whether indoor pet ownership entails...
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Optimization of Allergen Panels for Diagnosis of Allergic Rhinitis

Lee J, Kim JK, Kim KS, Rhee CS

The selection of allergen panel is very important to test for innumerable allergens throughout the Korea. However, the allergens studied are heterogeneous depending on the area the patient live and...
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Human ex vivo and in vitro disease models to study food allergy

Hung L, Obernolte , Sewald K, Eiwegger T

Food allergy is a growing global public health concern. As treatment strategies are currently limited to allergen avoidance and emergency interventions, there is an increasing demand for appropriate models of...
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Proper allergen selection for serum specific IgE test in children

Lee YJ, Yang HJ, Yoon JS, Han MY, Kim CK, Kim JT, and the Korean Academy of Pediatric Allergy and Respiratory Disease Research Executive Committee

Identifying allergic sensitization is important for the proper diagnosis and management of allergic diseases. Skin prick testing and measuring serum specific IgE antibodies are standard tests to confirm allergic sensitization....
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Tolerogenic Dendritic Cells Reduce Airway Inflammation in a Model of Dust Mite Triggered Allergic Inflammation

Aragão-França LS, Rocha VC, Cronemberger-Andrade A, Costa FH, Vasconcelos JF, Athanazio , Silva DN, Santos ES, Meira CS, Araújo CF, Cerqueira , Cardillo F, Alcântara-Neves NM, Soares MB, Pontes-de-Carvalho LC

PURPOSE: The use of tolerogenic dendritic cells (TolDCs) to control exacerbated immune responses may be a prophylactic and therapeutic option for application in autoimmune and allergic conditions. The objective of...
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Skin prick test reactivity to aeroallergens in adult allergy clinic in Thailand: a 12-year retrospective study

Oncham S, Udomsubpayakul U, Laisuan W

BACKGROUND: The global prevalence of allergic rhinitis, asthma, and atopic dermatitis has risen significantly over the last 2 decades. Allergic sensitization to aeroallergen is a major risk factor in developing...
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Comparison between Newly Developed and Commercial Inhalant Skin Prick Test Reagents Using In Vivo and In Vitro Methods

Lee SC, Sim DW, Lee J, Jeong KY, Park KH, Lee JH, Kim JD, Park JW

BACKGROUND: We developed skin prick test (SPT) reagents for common inhalant allergens that reflected the real exposure in Korea. The study aim was to evaluate diagnostic usefulness and allergen potency...
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Accuracy of serum-specific IgE test with microfluidic array enzyme-linked immunosorbent assay for diagnosing inhalant allergen sensitization in asthma and/or rhinitis allergy patients in Jakarta, Indonesia

Sinurat J, Rengganis , Rumende CM, Harimurti

BACKGROUND: Asthma and allergic rhinitis are a global health burden. Inhalant allergens worsen the symptoms and clinical manifestations of asthma and allergic rhinitis. Skin prick test is the gold standard...
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The International Study of the Allergic Rhinitis Survey: outcomes from 4 geographical regions

Passali D, Cingi C, Staffa P, Passali F, Muluk NB, Bellussi M

BACKGROUND: Allergic rhinitis (AR) is a global health problem and is characterised by one or more symptoms, including sneezing, itching, nasal congestion and rhinorrhea. OBJECTIVE: We investigated the features of AR...
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Detecting Allergens From Black Tiger Shrimp Penaeus monodon That Can Bind and Cross-link IgE by ELISA, Western Blot, and a Humanized Rat Basophilic Leukemia Reporter Cell Line RS-ATL8

Jarupalee , Chatchatee P, Komolpis K, Suratannon N, Roytrakul , Yingchutrakul Y, Yimchuen W, Butta P, Jacquet A, Palaga T

BACKGROUND: Black tiger shrimp Penaeus monodon is one of the common causes of shellfish allergy that is increasing worldwide. One of the important problems in the management of shellfish allergy...
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