- Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines
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Kim SH, Kuh SU, Kim KN, Park JY, Cho KH, Chin DK, Kim KS, Cho YE
- KMID: 2352817
- Yonsei Med J.
- 2015 Jan;56(1):277-286.
- doi: 10.3349/ymj.2015.56.1.277
PURPOSE: To investigate the molecular responses of various genes and proteins related to disc degeneration upon treatment with cytokines that affect disc-cell proliferation and phenotype in living human intervertebral discs... -
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- Msx2 mediates the inhibitory action of TNF-alpha on osteoblast differentiation
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Lee HL, Yi T, Woo KM, Ryoo HM, Kim GS, Baek JH
- KMID: 1078359
- Exp Mol Med.
- 2010 Jun;42(6):437-445.
- doi: 10.3858/emm.2010.42.6.045
TNF-alpha, a proinflammatory cytokine, inhibits osteoblast differentiation under diverse inflammatory conditions; however, the underlying mechanisms in terms of the TNF-alpha signaling pathway remain unclear. In this study, we examined the... -
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