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The effect of alanine aminotransferase dynamics on predicting sustained virological response in chronic hepatitis C virus infection

Kim TY

No abstract available.
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The Independent Effects of Cigarette Smoking, Alcohol Consumption, and Serum Aspartate Aminotransferase on the Alanine Aminotransferase Ratio in Korean Men for the Risk for Esophageal Cancer

Kimm H, Kim S, Jee SH

PURPOSE: The goal of this study is to assess the interactions among alcohol consumption, cigarette smoking, and aspartate aminotransferase (AST) / alanine aminotransferase (ALT) ratios on esophageal cancer. MATERIALS AND...
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Clinical impact of the early alanine amininotransferase flare during tenofovir monotherapy in treatment-naïve patients with chronic hepatitis B

Seo HY, Lee HA, Ko SY, Wang JH, Kim JH, Choe WH, Kwon SY

BACKGROUND/AIMS: Little is known about the effect of early flares on response during first-line tenofovir disoproxil fumarate (TDF) treatment for chronic hepatitis B (CHB). The aim of this study was...
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Abnormal Liver Function Tests in Pregnancy: A Single Institution Experience

Kim JH, Kwon CI, Ko EH, Kim DY, Kim HY, Jung SH, Ko KH, Hong SP, Shin SJ, Hwang SG, Park PW, Rim KS

  • KMID: 782884
  • Korean J Gastroenterol.
  • 2007 Jul;50(1):36-41.
BACKGROUND/AIMS: Elevated transaminase levels are often detected during pregnancy. Causes are variable and difficult to differentiate. Furthermore, there is no practical guideline for abnormal transaminase levels in pregnancy. The...
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Dose-Response Relationship between Alanine Aminotransferase Levels within the Reference Interval and Metabolic Syndrome in Chinese Adults

Wu P, Chen Q, Chen L, Zhang P, Xiao J, Chen X, Liu M, Wang S

PURPOSE: Elevation in serum alanine aminotransferase (ALT) levels is a biomarker for metabolic syndrome (MS); however, the relationship has not been fully investigated within the reference interval of ALT levels....
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A Novel Model for Predicting Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B and Normal Alanine Aminotransferase Levels

Sinn DH, Lee JH, Kim K, Ahn JH, Lee JH, Kim JH, Lee DH, Yoon JH, Kang W, Gwak GY, Paik YH, Choi MS, Lee JH, Koh KC, Paik SW

BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) can develop in chronic hepatitis B (CHB) patients with normal alanine aminotransferase (ALT) levels. Therefore, methods that can stratify an individual's HCC risk are needed. METHODS: A...
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The Relationship of Histologic Activity to Serum ALT, HCV genotype and HCV RNA titers in Chronic Hepatitis C

Lee YS, Yoon SK, Chung ES, Bae SH, Choi JY, Han JY, Chung KW, Sun HS, Kim BS, Kim BK

It is unclear whether serum ALT levels or virological characteristics of hepatitis C virus(HCV) including HCV genotypes and HCV RNA titers, can reflect the degree of histological injury in chronic...
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Elevation of Serum Aminotransferase Levels and Future Risk of Death from External Causes: A Prospective Cohort Study in Korea

Sohn J, Kang DR, Kim HC, Cho J, Choi YJ, Kim C, Suh I

PURPOSE: The association between liver enzymes and death from external causes has not been examined. We investigated the association between serum aminotransferase levels and external-cause mortality in a large prospective...
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Hepatocellular Carcinoma Risk of Compensated Cirrhosis Patients with Elevated HBV DNA Levels according to Serum Aminotransferase Levels

Lee J, Sinn DH, Kim JH, Gwak GY, Kim HS, Jung SH, Paik YH, Choi MS, Lee JH, Koh KC, Yoo BC, Paik SW

Sometimes, hepatitis B virus (HBV)-related cirrhotic patients with normal aminotransferase levels are closely followed-up for the elevation of aminotransferase levels instead of prompt antiviral therapy (AVT). We analyzed the long-term...
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Intron 4 VNTR (4a/b) Polymorphism of the Endothelial Nitric Oxide Synthase Gene Is Associated with Breast Cancer in Mexican Women

Ramirez-Patino R, Figuera LE, Puebla-Perez AM, Delgado-Saucedo JI, Legazpi-Macias MM, Mariaud-Schmidt RP, Ramos-Silva A, Gutierrez-Hurtado IA, Gomez Flores-Ramos L, Zuniga-Gonzalez GM, Gallegos-Arreola MP

The endothelial nitric oxide synthase (eNOS) gene plays an important role in several biological functions. Polymorphisms of the eNOS gene have been associated with cancer. It has been suggested that...
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Association of serum alanine aminotransferase and gamma-glutamyltransferase levels within the reference range with metabolic syndrome and nonalcoholic fatty liver disease

Oh HJ, Kim TH, Sohn YW, Kim YS, Oh YR, Cho EY, Shim SY, Shin SR, Han AL, Yoon SJ, Kim HC

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) has recently been found to be a novel component of metabolic syndrome (MS), which is one of the leading causes of chronic liver disease....
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Rapid normalization of alanine aminotransferase predicts viral response during combined peginterferon and ribavirin treatment in chronic hepatitis C patients

Kim YJ, Jang BK, Kim ES, Park KS, Cho KB, Chung WJ, Hwang JS

BACKGROUND/AIMS: The treatment for chronic hepatitis C (CHC) is removal of the virus in order to prevent progression to liver cirrhosis and hepatocellular carcinoma (HCC). Few data have been presented...
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The Relationship Between Serum Adiponectin Level and Serum Alanine Aminotransferase Elevation in Korean Male with Nonalcoholic Fatty Liver Disease

Lee YS, Cho YK, Pae JC, Oh SY, Kang MS, Park JH, Kim HJ, Park DI, Sohn CI, Jeon WK, Kim BI, Lee WY, Oh KW, Yun EJ, Oh ES

  • KMID: 760649
  • Korean J Hepatol.
  • 2006 Jun;12(2):221-229.
BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) comprises a large part of chronic liver diseases. Recently it was reported that adipokines are closely associated with the common risk factors for...
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Serum ALT and HBV DNA Levels in Patients with HBeAg-Negative Chronic Hepatitis B

Kim KH, Na IH, Cha JM, Cho YK, Park SY, Kim HP, Song CS, Heo J, Cho M

  • KMID: 1085301
  • Korean J Hepatol.
  • 2003 Dec;9(4):284-292.
BACKGROUND/AIMS: HBeAg-negative chronic hepatitis B (CHB) has a poor long-term prognosis. Since no precise clinically relevant HBV thresholds are known in HBeAg-negative CHB, the decision to treat is difficult....
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Comparison on the Efficacy and Safety of Biphenyl Dimethyl Dicarboxylate and Ursodeoxycholic Acid in Patients with Abnormal Alanine Aminotransferase: Multicenter, Double-blinded, Randomized, Active-controlled Clinical Trial

Lee SH, Cheon GJ, Kim HS, Kim YD, Kim SG, Kim YS, Jeong SW, Jang JY, Kim BS

BACKGROUND/AIMS: Chronic hepatocellular damage is closely associated with hepatic fibrosis and fatal complication in most liver diseases. The aim of this study is to compare the efficacy and safety of...
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Normal Serum Aminotransferase Levels and the Metabolic Syndrome: Korean National Health and Nutrition Examination Surveys

Kim HC, Choi KS, Jang YH, Shin HW, Kim DJ

Increasing evidence suggests an association between elevated serum aminotransferase level and the metabolic syndrome. However, the significance of relatively low levels of aminotransferase in relation to the metabolic syndrome has...
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Metabolic Characteristics and Associated Factors of Nonalcoholic Fatty Liver Disease Diagnosed at Medical Checkups

Nah EH, Park JY

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) has been reported to be related with metabolic disorder and frequently accompanied by abnormal liver function. This study was performed to investigate the metabolic...
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The Diagnostic Value of Serum Hyaluronic Acid, 7S Domain of Type IV Collagen and AST/ALT Ratio as Markers of Hepatic Fibrosis in Chronic Hepatitis B and Cirrhosis Patients

Park JH, Park CK, Kim ES, Park SY, Jo CM, Tak WY, Kweon YO, Kim SK, Choi YW

  • KMID: 863141
  • Korean J Hepatol.
  • 2003 Jun;9(2):79-88.
BACKGROUND/AIMS: The prognosis of chronic liver disease is closely related to the development of hepatic fibrosis. Liver biopsy is the gold standard method to assess inflammatory activity and fibrosis...
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Pretreatment ALT Level and Histologic Activity as Predictors of HBeAg Loss in Lamivudine Treatment for Chronic Hepatitis B

Kweon YO, Kang KH

  • KMID: 760529
  • Korean J Hepatol.
  • 2004 Mar;10(1):31-41.
BACKGROUND/AIMS: Lamivudine is a potent inhibitor of hepatitis B virus replication, but an increased incidence of YMDD mutation may be associated with its long term use. Thus, the decision...
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Clinical Efficacy of AST/ALT Ratio and Platelet Counts as Predictors of Degree of Fibrosis in HBV Infected Patients without Clinically Evident Liver Cirrhosis

Park SY, Kang KH, Park JH, Lee JH, Cho CM, Tak WY, Kweon YO, Kim SK, Choi YH

  • KMID: 772633
  • Korean J Gastroenterol.
  • 2004 Apr;43(4):246-251.
BACKGROUND/AIMS: Hepatic fibrosis is an important prognostic factor in chronic hepatitis B. Liver biopsy is a gold standard diagnostic tool but an invasive procedure, so it cannot be done...
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