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Detection of Autoantibodies against Aquaporin-1 in the Sera of Patients with Primary Sjögren's Syndrome

Alam J, Choi YS, Koh JH, Kwok SK, Park SH, Song YW, Park K, Choi Y

The pathophysiology of glandular dysfunction in Sjögren's syndrome (SS) has not been fully elucidated. Previously, we reported the presence of autoantibodies to AQP-5 in patients with SS, which was associated...
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Potential Role of Bacterial Infection in Autoimmune Diseases: A New Aspect of Molecular Mimicry

Alam J, Kim YC, Choi Y

Molecular mimicry is an attractive mechanism for triggering autoimmunity. In this review, we explore the potential role of evolutionary conserved bacterial proteins in the production of autoantibodies with focus on...
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N-acetylcysteine and the human serum components that inhibit bacterial invasion of gingival epithelial cells prevent experimental periodontitis in mice

Alam J, Baek KJ, Choi YS, Kim YC, Choi Y

PURPOSE: We previously reported that human serum significantly reduces the invasion of various oral bacterial species into gingival epithelial cells in vitro. The aims of the present study were to...
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