- Inhibition of indoxyl sulfate-induced intrarenal renin-angiotensin system activation: targeting the aryl hydrocarbon receptor
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Akbar MF
- KMID: 2390929
- Transl Clin Pharmacol.
- 2017 Sep;25(3):114-116.
- doi: 10.12793/tcp.2017.25.3.114
Indoxyl sulfate, a protein-bound uremic toxin, leads to CKD (chronic kidney disease) progression and its complications through the activation of AhR (aryl hydrocarbon receptor) and RAS (renin-angiotensin system). Inhibition of... -
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