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Immortalization of human embryonic fibroblasts by overexpression of c-myc and simian virus 40 large T antigen

Kim HS, Shin JY, Yun JY, Ahn DK, Lee JY

  • KMID: 1457544
  • Exp Mol Med.
  • 2001 Dec;33(4):293-298.
SV40 large T antigen, a viral oncoprotein, is known to immortalize human diploid fibroblast by soaking up cellular RB and p53, but its frequency is extremely low. Additional genetic alteration...
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Age-dependent dichotomous effect of superoxide dismutase Ala16Val polymorphism on oxidized LDL levels

Dedoussis , Kanoni S, Panagiotakos DB, Louizou E, Grigoriou , Chrysohoou C, Pitsavos C, Stefanadis C

We investigated the association between superoxide dismutase (SOD) Ala16Val polymorphism and the levels of oxidized LDL lipoprotein-C (ox-LDL-C) in two age-different Greek cohorts. Four hundred fifteen middle-aged (n=147 females: 43.2+/-13...
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