- Swim training improves leptin receptor deficiency-induced obesity and lipid disorder by activating uncoupling proteins
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Oh KS, Kim EY, Yoon M, Lee CM
- KMID: 1047090
- Exp Mol Med.
- 2007 Jun;39(3):385-394.
Leptin receptor deficiency causes morbid obesity and hyperlipidemia in mice. Since physical exercise enhances energy expenditure, it is an important part of successful weight-control regimens. We investigated the mechanism by... -
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- Insulin Resistance in Non-Alcoholic Fatty Liver Disease
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Park JH
- KMID: 760627
- Korean J Hepatol.
- 2006 Mar;12(1):16-30.
Insulin resistance is the pathophysiological hallmark of various kinds of clinical diseases, including non- alcoholic fatty liver disease. Insulin resistance is the common characteristic of metabolic syndrome and its related... -
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- Surgical removal of visceral fat decreases plasma free fatty acid and increases insulin sensitivity on liver and peripheral tissue in monosodium glutamate (MSG)-obese rats
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Kim YW, Kim JY, Lee SK
- KMID: 646022
- J Korean Med Sci.
- 1999 Oct;14(5):539-545.
- doi: 10.3346/jkms.1999.14.5.539
In order to evaluate the role of visceral and subcutaneous fat tissue in insulin sensitivity and lipid metabolism, we measured the fasting levels of plasma free fatty acid (FFA) and... -
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- Enhanced A-FABP expression in visceral fat: potential contributor to the progression of NASH
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Yoon MY, Sung JM, Song CS, Lee WY, Rhee EJ, Shin JH, Yoo CH, Chae SW, Kim JY, Jin W, Cho YK
- KMID: 1392907
- Clin Mol Hepatol.
- 2012 Sep;18(3):279-286.
- doi: 10.3350/cmh.2012.18.3.279
BACKGROUND/AIMS: Adipose tissue is an active endocrine organ that secretes various metabolically important substances including adipokines, which represent a link between insulin resistance and nonalcoholic steatohepatitis (NASH). The factors responsible... -
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- Effect of Weight Reduction on Metabolic Syndrome in Korean Obese Patients
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Park HS, Sim SJ, Park JY
- KMID: 1733477
- J Korean Med Sci.
- 2004 Apr;19(2):202-208.
- doi: 10.3346/jkms.2004.19.2.202
The Third Report of the National Cholesterol Education Program Adult Treatment Panel III emphasized the importance of management of the metabolic syndrome. However, little information is available about the effect... -
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- Determination of Roxithromycin by Liquid Chromatography/Mass Spectrometry after Multiple-Dose Oral Administration in Broilers
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Lim JH, Park BK, Yun HI
- KMID: 1099819
- J Vet Sci.
- 2003 Apr;4(1):35-39.
A highly sensitive and specific method for the determination of roxithromycin in broiler tissues by LC/MS was developed and validated. A dichloromethane extract of the sample was separated on C18... -
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- Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes
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Jeon MJ, Leem J, Ko MS, Jang JE, Park HS, Kim HS, Kim M, Kim EH, Yoo HJ, Lee CH, Park IS, Lee KU, Koh EH
- KMID: 1389736
- Exp Mol Med.
- 2012 Sep;44(9):562-570.
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER stress response, resulting... -
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- Phenotype of peroxisome proliferator-activated receptor-alpha(PPARalpha)deficient mice on mixed background fed high fat diet
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Kim BH, Won YS, Kim EY, Yoon M, Nam KT, Oh GT, Kim DY
- KMID: 1089604
- J Vet Sci.
- 2003 Dec;4(3):239-244.
Considerable controversy exists in determining the role of peroxisome proliferator-activated receptor-alpha(PPARalpha) on obesity. Previous reports demonstrated that PPARalpha is a critical modulator of lipid homeostasis, but the overt, obese phenotypic... -
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- Nonalcoholic steatohepatitis: Pathogenesis and treatment
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Park SH
- KMID: 1073326
- Korean J Hepatol.
- 2008 Mar;14(1):12-27.
- doi: 10.3350/kjhep.2008.14.1.12
Nonalcoholic fatty liver disease (NAFLD) is characterized by a wide spectrum of liver damage spanning steatosis, nonalcoholic steatohepatitis (NASH), cryptogenic liver cirrhosis, and even to hepatocellular carcinoma. Investigations in the... -
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