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Resistance to local anesthesia in people with the Ehlers-Danlos Syndromes presenting for dental surgery

Schubart J, Schaefer E, Janicki P, Adhikary S, Schilling , Hakim AJ, Bascom R, Francomano CA, Raj SR

BACKGROUND: People with the Ehlers-Danlos Syndromes (EDS), a group of heritable disorders of connective tissue, often report experiencing dental procedure pain despite local anesthetic (LA) use. Clinicians have been uncertain...
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