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Anti-adhesive effect and safety of a thermosensitive adhesion barrier (Mediclore) for thyroid surgery: a double-blinded randomized controlled trial

Ahn Jh, Yoon SG, Yi JW, Kim Sj, Lee KE

Purpose: Postoperative adhesions after thyroidectomy adversely affect patients’ quality of life. This study assessed the anti-adhesive effect and safety of thermosensitive sol-gel agents for patients undergoing thyroidectomy. Methods: A double-blind parallel-group...
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GPR40 Agonism Modulates Inflammatory Reactions in Vascular Endothelial Cells

Kim JW, Roh E, Choi KM, Yoo HJ, Hwang HJ, Baik SH

Endothelial dysfunction is strongly linked with inflammatory responses, which can impact cardiovascular disease. Recently, G protein-coupled receptor 40 (GPR40) has been investigated as a modulator of metabolic stress; however, the...
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Expression of ICAM-1 in Blood Vascular Endothelium and Tissues in Human Premalignant Lesion and Gastric/Hepatocellular Carcinomas

Kang L, Kim M, Lee YM

Background/Aims: Angiogenesis is essential for the outgrowth and metastasis of tumors. The structure and characteristics of tumor vasculature differ from those of normal vessels. We compared the characteristics of differentially...
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Clinical application of a new hemostatic material using mussel-inspired catecholamine hemostat: A pilot study

Park YM, Seo HI, Kim JH, Yoon SP, Lee H, Lee MS

Backgrounds/Aims: This study aimed to evaluate clinical application of InnoSEAL Plus (a mussel-inspired catecholamine hemostat) as a new hemostatic material for humans. Methods: Patients treated with topical hemostatic patches after liver...
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Adhesion of External Iliac Vessels Found in a Modified Stoppa Approach to Acetabular Fracture in a Patient with a History of Previous Abdominal Surgery

Kim ST, Shin S, Lee H, Jeon SM

Some structures should be noted in the modified Stoppa approach for the treatment of acetabular fractures. Among them, the external iliac vessels should be protected with special care during surgery....
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Treadmill Exercise Ameliorates Short-term Memory Impairment by Suppressing Hippocampal Neuroinflammation in Poloxamer-407-Induced Hyperlipidemia Rats

Park SS, Kim TW, Sung YH, Park YJ, Kim MK, Shin MS

Purpose: Poloxamer-407 (P-407) is used to induce hyperlipidemia. Exercise is effective in improving arteriosclerosis and cognitive impairment. In this research, the effect of treadmill running on short-term memory in the...
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A multicenter, prospective, randomized clinical trial of marine mussel-inspired adhesive hemostatic materials, InnoSEAL Plus

Choi GS, Kim SH, Seo HI, Ryu JH, Yun SP, Koh MY, Lee MS, Lee H, Kim JH

Purpose: InnoSEAL Plus is an adhesive, coagulant-free hemostatic material that mimics the adhesion mechanism of marine mussels. This study reports on the safety and efficacy of InnoSEAL Plus for patients...
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Effects of anchoring sutures at diverting ileostomy after rectal cancer surgery on peritoneal adhesion at following ileostomy reversal

Choi ET, Lim SB, Lee JL, Kim CW, Kim YI, Yoon YS, Park IJ, Yu CS, Kim JC

Purpose: During diverting ileostomy reversal for rectal cancer patients who underwent previous sphincter-saving surgery, the extent of adhesion formation around the ileostomy site affects operative and postoperative outcomes. Anchoring sutures...
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Feasibility of the Gastrografin Challenge for Adhesive Small Bowel Obstruction

Jung KS, Choi KJ, Yoon KW, Yoo KS, Gil EM, Park CM

Purpose: This retrospective study investigated the feasibility, diagnostic, and therapeutic advantages of the gastrografin challenge on patients with adhesive small bowel obstruction (ASBO). Methods: There were 125 patients reviewed who...
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Successful electrode insertion for spinal cord stimulation after balloon adhesiolysis in a patient with epidural adhesion - A case report -

Hyun DM, Park CH, Kim Y, Choi SS

Background: Spinal cord stimulation (SCS) can be successfully performed using highly developed implantation techniques. However, anatomical barriers, such as epidural adhesion, may impede placing the electrode for SCS in an...
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Sulforaphane Inhibits ICAM-1 Expression and Monocyte Adhesion in Human Bladder Cancer T24 Cells

Ahn KY, Khoi PN, Cho YS, Li S, Sah DK, Xia Y, Jung YD

Intracellular adhesion molecule-1 (ICAM-1) belongs to the immunoglobulin-like superfamily of adhesion molecules that mediate cell adhesion to other cells, and ICAM-1 is involved in cancer progression and recurrence. Since the...
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Advances in the Development of Anti-Adhesive Biomaterials for Tendon Repair Treatment

Zhou H, Lu H

BACKGROUND: Peritendinous adhesion that simultaneous with tendon healing link the healing tendon to the surrounding tissue. It results in functional disability, and has a significant adverse impact on health as...
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An additional lysis procedure during arthrocentesis of the temporomandibular joint

Lee KM, Jang WH, You MS, Lee BK

Background: Arthrocentesis of the temporomandibular joint (TMJ) is an easy, highly efficient, minimally invasive procedure for treating temporomandibular joint disorders (TMDs). However, in some cases of mouth opening limitation (MOL),...
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Feasibility and safety of fertilitysparing surgery in epithelial ovarian cancer with dense adhesion: a longterm result from a single institution

Baek MH, Park JY, Kim DY, Suh DS, Kim JH, Kim YM, Kim YT

Objective: We investigated the feasibility and safety of fertility-sparing surgery (FSS) in patients with epithelial ovarian cancer (EOC) with dense adhesions. Methods: Patients were divided into cases with and without dense...
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Spontaneous Resolution of Cataract-related Acute Vitreomacular Traction Syndrome

Lee SH, Jeon SH, Roh YJ

Purpose: To report a case of spontaneous resolution of vitreomacular traction (VMT) syndrome after cataract surgery. Case summary: A 70-year-old woman underwent lens emulsification and intraocular lens implantation for a right-eye...
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Inhibition of Smooth Muscle Cell Proliferation and Migration by a Talin Modulator Attenuates Neointimal Formation after Femoral Arterial Injury

Lim IR, Kim C, Jung JW, Kim JH, Hong SJ

Background and Objectives: Vascular smooth muscle cell (SMC) proliferation and migration play a critical role in neointimal formation. Focal adhesion is involved in cell proliferation and migration, and talin is...
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Loosening of the mesothelial barrier as an early therapeutic target to preserve peritoneal function in peritoneal dialysis

Kang DH

Phenotype transition of peritoneal mesothelial cells (MCs) including the epithelial-to-mesenchymal transition (EMT) is regarded as an early mechanism of peritoneal dysfunction and fibrosis in peritoneal dialysis (PD), producing proinflammatory and...
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Does Laparoscopic Adhesiolysis Reduce the Risk of Small Bowel Obstruction Related Readmissions and Reoperations Compared to Open Adhesiolysis?

Park JH, Kim DJ, Park JH

Purpose: The present study aimed to assess the safety and efficacy of laparoscopic adhesiolysis in decreasing recurrent episodes of small bowel obstruction (SBO) compared to that of the conventional open...
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Laparoscopic Adhesiolysis for Small Bowel Obstruction: Effective Alternatives or Immoderate Challenge?

Kang BM

Laparoscopic lysis for intraperitoneal adhesion should be performed only in selective patients with small bowel obstruction by experienced surgeons. Current evidence is insufficient to postulate that laparoscopic surgery is safe...
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Endometrial profilin 1: a key player in embryo-endometrial crosstalk

Lee CJ, Hong SH, Yoon MJ, Lee KA, Ko JJ, Koo HS, Kim JH, Choi DH, Kwon H, Kang YJ

Objective: Despite extensive research on implantation failure, little is known about the molecular mechanisms underlying the crosstalk between the embryo and the maternal endometrium, which is critical for successful pregnancy....
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