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Opening of ATP-sensitive K+ channel by pinacidil requires serine/threonine phosphorylation in rat ventricular myocytes

Kwak YG, Chae SW

  • KMID: 2285223
  • Korean J Physiol Pharmacol.
  • 1999 Jun;3(3):293-303.
The influences of specific protein phosphatase and protein kinase inhibitors on the ATP-sensitive K+ (KATP) channel-opening effect of pinacidil were investigated in single rat ventricular myocytes using patch clamp technique. In cell-attached patches,...
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Modulation of ATP-induced activation of the muscarinic K+ channel activity by protein kinase C

Kim YM, Park HK, Han JH, Park CO, Hong SG

  • KMID: 2071833
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):743-753.
The atrial acetylcholine-activated K+ (KACh) channel is gated by the pertussis toxin-sensitive inhibitory G (GK) protein. Earlier studies revealed that ATP alone can activate the KACh channel via transphosphorylation mediated by nucleoside-diphosphate kinase...
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