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Development of a packaging cell line for propagation of replication-deficient adenovirus vector

Kim JS, Lee SH, Cho YS, Park KS, Kim YH, Lee JH

  • KMID: 938878
  • Exp Mol Med.
  • 2001 Sep;33(3):145-149.
A human embryonic kidney cell line 293 is widely used for adenovirus production and propagation. With this cell line, however, replication-competent virus (RCV) is frequently generated, especially during large-scale production...
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