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Clinical and Laboratory Predictors associated with Complicated Scrub Typhus

Kim MH, Kim SH, Choi JH, Wie SH

BACKGROUND: Scrub typhus, a mite-borne disease caused by bites of Orientia tsutsugamushi-infected chiggers, is endemic in Asia-Pacific countries. In Korea, it is a seasonal disease prevalent in autumn and one...
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Qualitative and Quantitative Comparison of Contrast-Enhanced Fluid-Attenuated Inversion Recovery, Magnetization Transfer Spin Echo, and Fat-Saturation T1-Weighted Sequences in Infectious Meningitis

Azad R, Tayal M, Azad S, Sharma G, Srivastava RK

OBJECTIVE: To compare the contrast-enhanced fluid-attenuated inversion recovery (CE-FLAIR), the CE T1-weighted (CE-T1W) sequence with fat suppression (FS) and magnetization transfer (MT) for early detection and characterization of infectious meningitis. MATERIALS...
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Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer

Lee SH, Kim HP, Kang JK, Song SH, Han SW, Kim TY

PURPOSE: RNA editing generates protein diversity by altering RNA sequences in coding regions without changing the overall DNA sequence. Adenosine-to-inosine (A-to-I) RNA editing events have recently been reported in some...
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Tuberculous Meningitis-Mimicking Varicella-Zoster Meningitis

Hong SI, Kim T, Jung J, Park SY, Chong YP, Lee SO, Choi SH, Kim YS, Woo JH, Lee SA, Kim SH

BACKGROUND: Varicella-zoster virus (VZV) is one of the most common etiologies of aseptic meningitis. The severest manifestation of VZV meningitis is occasionally confused with tuberculous meningitis (TBM). Thus, we investigated...
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Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages

Bae MJ, Ryu S, Kim HJ, Cha SI, Kim CH, Lee J

BACKGROUND: Delayed hypersensitivity plays a large role in the pathogenesis of tuberculous pleural effusion (TPE). Macrophages infected with live Mycobacterium tuberculosis (MTB) increase the levels of adenosine deaminase2 (ADA2) in...
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Myelomatous Pleural Effusion with Elevated ADA Activity

Moon HJ, Shin DY, Kim HR, Park YW, Woo SM, Cha JH, Han KH

Multiple myeloma is a plasma cell neoplasm mainly involving the bone marrow and skeletal system. Myelomatous pleural effusion is rare, accounting for less than 1%. In cases with high adenosine...
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Assessment of immunological markers and booster effects of Ag85B peptides, Ag85B, and BCG in blood of BCG vaccinated children: a preliminary report

Husain AA, Daginawla , Singh L, Kashyap RS

PURPOSE: In the present study, the protective immunological markers in serum and peripheral blood mononuclear cells (PBMCs) of bacillus Calmette-Guerin (BCG) vaccinated and unvaccinated children were evaluated after vaccination. Further,...
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A Case of Disseminated Cryptococcosis Mimicking Lung Cancer and Prostate Cancer in an Immunocompetent Patient: A Review of the Literature

Lee Y, Kim JH, Seo H, Park H, Oh YM, Lee SD, Lee JS

Cryptococcosis can occur in immunocompetent patients; in fact, it accounts for 20% of all cryptococcal infections. In immunocompetent patients, although clinical symptoms may not be obvious, cryptococcosis should be considered...
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Malignant mesothelioma mistaken for tuberculous pleurisy

Yang JY, Song MJ, Park SJ, Cheon J, Yoo JW, Choi CM, Kim YH

Malignant mesothelioma is a common, primary tumor that can invade pleura, and is associated with previous exposure to asbestos. However, it poses considerable difficulties regarding its diagnosis and treatment, and...
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Single Pleural Relapse of a Nasal-Type Extranodal Natural Killer/T-Cell Lymphoma: A Case Report

Kim K, Oh Y, Lim SN, Choi SY, Lee OJ, Choe KH, Lee KM, An JY

  • KMID: 2320504
  • Tuberc Respir Dis.
  • 2014 Apr;76(4):184-187.
A nasal-type extranodal natural killer/T-cell lymphoma is considered an aggressive form of non-Hodgkin's lymphoma, with approximately half of all patients relapsing during the follow-up period, and most relapses occurring within...
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A Case of Pleural Paragonimiasis Confused with Tuberculous Pleurisy

Song J, Hong G, Song JU, Kim W, Han SG, Ko Y, Chang B, Jeong BH, Eom JS, Lee JH, Jhun BW, Jeon K, Kim HK, Koh WJ

  • KMID: 2320502
  • Tuberc Respir Dis.
  • 2014 Apr;76(4):175-178.
Here, we report a case of pleural paragonimiasis that was confused with tuberculous pleurisy. A 38-year-old man complained of a mild febrile sensation and pleuritic chest pain. Radiologic findings showed...
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Tuberculous Pleurisy: An Update

Jeon D

  • KMID: 2320498
  • Tuberc Respir Dis.
  • 2014 Apr;76(4):153-159.
Tuberculous pleurisy is the most common form of extrapulmonary tuberculosis in Korea. Tuberculous pleurisy presents a diagnostic and therapeutic problem due to the limitations of traditional diagnostic tools. There have...
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Interferon-gamma Release Assay Using Pericardial Fluid and Peripheral Blood for the Diagnosis of Tuberculous Pericarditis: A Case Report

Park KS, Park HD, Ki CS, Lee NY, Chang SA, Kang ES

  • KMID: 2312252
  • Lab Med Online.
  • 2014 Apr;4(2):116-121.
Here, we report a case in which the rapid diagnosis of tuberculous pericarditis was made using Mycobacterium tuberculosis (MTB)-specific interferon-gamma release assay on peripheral blood and pericardial effusion. Acid-fast bacilli...
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Diagnosis and treatment of extrapulmonary tuberculosis

Kim SH

Diagnosing extrapulmonary tuberculosis (E-TB) remains a challenge because clinical samples obtained from sites that are not easily accessible are sometimes paucibacillary, decreasing the sensitivity of diagnostic tests. Adenosine deaminase (ADA)...
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Predictive Performance of Serum Procalcitonin for the Diagnosis of Bacterial Meningitis after Neurosurgery

Choi SH, Choi SH

BACKGROUND: Postoperative bacterial meningitis (PBM) is a serious potential complication after neurosurgery. Early diagnosis and introduction of antimicrobial therapy are necessary to reduce the rate of fatal outcomes from PBM....
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Association between Elevated Pleural Interleukin-33 Levels and Tuberculous Pleurisy

Lee KS, Kim HR, Kwak S, Choi KH, Cho JH, Lee YJ, Lee MK, Lee JH, Park SD, Park DS

BACKGROUND: Interferon-gamma (IFN-gamma) plays a crucial role in Mycobacterium tuberculosis induced pleural responses. Interleukin (IL)-33 up-regulates the production of IFN-gamma. We aimed to identify whether an association between pleural IL-33...
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Usefulness of Pleural Adenosine Deaminase in Children for the Differentiation Tuberculous Pleural Effusion from Mycoplasma pneumonia with Pleural Effusion

Choi JH, Hur WK, Baek HS, Oh JW, Lee HB

  • KMID: 2315305
  • Pediatr Allergy Respir Dis.
  • 2012 Dec;22(4):404-410.
PURPOSE: Determination of adenosine deaminase (ADA) in pleural fluid has been suggested as another tool to establish early diagnosis of tuberculous pleural effusion. However, there are few studies concerning its...
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Sarcoidosis Presenting with Massive Pleural Effusion and Elevated Serum and Pleural Fluid Carbohydrate Antigen-125 Levels

Lee IS, Kim SB, Moon CS, Jung SM, Kim SY, Kim EY, Jung JY, Kang YA, Kim YS, Kim SK, Chang J, Park MS

A 55-year-old woman was admitted for an elevated serum carbohydrate antigen-125 (CA-125) level, and a left pleural effusion, which were detected at a routine health examination. Computed tomography of the...
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Comparison of Six Clinical Chemistry Test Results According to the Treatment of EDTA Anticoagulant in Body Fluid Specimens

Lee D, Jang JY, Yoon KR, Kim H, Uh Y, Kim J, Yoon KJ

  • KMID: 1426758
  • J Lab Med Qual Assur.
  • 2012 Dec;34(2):87-92.
BACKGROUND: Specimen requirements such as type of anticoagulant and number of tube for body fluid analysis vary with specimen type and requested laboratory tests. We compared the results of six...
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The Ratio Between the Percentage of Lymphocytes and Glucose Levels in Pericardial Fluid as a Method to Diagnose Tuberculous Pericarditis

Yang KH, Song YS, Jung SH, Kim TJ, Yoon SE, Jeong YS, Cho KH, Kim YB

  • KMID: 2264564
  • Korean J Med.
  • 2012 Oct;83(4):458-467.
BACKGROUND/AIMS: Adenosine deaminase (ADA) is a valuable biochemical marker for pericardial effusion (PE) and may be useful for diagnosing tuberculous pericarditis (TPE) in patients with PE. However, no definite cut-off...
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