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Efficacy of perineural versus intravenous dexamethasone in prolonging the duration of analgesia when administered with peripheral nerve blocks: a systematic review and meta-analysis

Tan ESJ, Tan YR, Liu CWY

Background: Perineural dexamethasone has been regarded as a promising adjunct for prolonging the duration of nerve blocks. However, it is uncertain whether its effects are due to local effects on...
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Approaching trauma analgesia using prolonged and novel continuous peripheral nerve blocks - A case report -

Ly E, Velamuri S, Hickerson W, Hill DM, Desai J, Tsui B, Herr M, Jones J

Background: A supraclavicular brachial plexus nerve block provides analgesia for the shoulder, arm, and hand; however, the maximum safe duration for a continuous infusion remains controversial. A novel continuous peripheral...
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Comparison of landmark and real-time ultrasound-guided epidural catheter placement in the pediatric population: a prospective randomized comparative trial

Mital T, Kamal M, Kumar M, Kumar R, Bhatia P, Singariya G

Background: Epidural block placement in pediatric patients is technically challenging for anesthesiologists. The use of ultrasound (US) for the placement of an epidural catheter has shown promise. We compared landmark-guided...
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Comeback of ketamine: resurfacing facts and dispelling myths

Kumar A, Kohli A

Initially known as CI-581, ketamine was first synthesized in 1962 as a replacement from phencyclidine. It has since been used as an anesthetic and analgesic. In addition, it has bronchodilating,...
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Postoperative Pain Management Status led by Nurse of Acute Pain Service

Kang MR, Ryu JO, Kim MH, Yun HS, Kwon JS

Purpose: This study was conducted to demonstrate objective stability of postoperative pain management status managed by nurse-based, anesthesiologist-supervised Acute Pain Service (APS). Methods: A retrospective descriptive review was conducted with...
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Rhomboid intercostal and subserratus plane block -a case series-

Elsharkawy H, Hamadnalla H, Altinpulluk EY, Gabriel RA

Background: The rhomboid intercostal and subserratus plane (RISS) block is a new interfascial block technique that has shown promising results for abdominal and thoracic surgeries. Our objective was...
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Effect of intraperitoneally administered propentofylline in a rat model of postoperative pain

Choi GJ, Kang H, Lee JM, Baek CW, Jung YH, Woo YC, Do JH, Ko JS

Background: In this study, we sought to evaluate whether systemic propentofylline (PPF) has antiallodynic effects in a rat model of postoperative pain, and to assess the mechanism involved. Methods: After plantar...
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The relative analgesic value of a femoral nerve block versus adductor canal block following total knee arthroplasty: a randomized, controlled, double-blinded study

Gadsden JC, Sata S, Bullock WM, Kumar AH, Grant SA, Dooley JR

Background: Multiple comparative studies report that adductor canal blocks provide similar pain relief to femoral nerve blocks following total knee arthroplasty. However, adductor canal blockade fails to anesthetize several important...
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Subcoracoid tunnel block as an alternative infraclavicular brachial plexus approach -a case series-

Diwan S, Sethi D, Gaikwad A, Sancheti P, Nair A

Background: Magnetic resonance neurography shows the brachial plexus cords in the subcoracoid tunnel beneath the pectoralis minor. With an ultrasound scan along the brachial line, the brachial plexus cords in...
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The role of regional analgesia in personalized postoperative pain management

Chitnis SS, Tang R, Mariano ER

Pain management plays a fundamental role in enhanced recovery after surgery pathways. The concept of multimodal analgesia in providing a balanced and effective approach to perioperative pain management is widely...
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Erector spinae plane block and altered hemostasis: is it a safe option? -a case series-

Galacho J, Veiga M, Ormonde L

Background: We described 5 cases of uneventful administration of the erector spinae plane (ESP) block to patients with altered hemostasis. Case: Five patients were admitted to the intensive care unit with...
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Association of trainee involvement in an acute pain service with postoperative opioid use in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy

Said ET, Sztain JF, Martin EI, Abramson WB, Meineke MN, Furnish TJ, Swisher MW, Gabriel RA

Background: Several hospitals have implemented a multidisciplinary Acute Pain Service (APS) to execute surgery-specific opioid sparing analgesic pathways. Implementation of an anesthesia attending-only APS has been associated with decreased postoperative...
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Ultrasound-guided percutaneous intercostal cryoanalgesia for multiple weeks of analgesia following mastectomy: a case series

Gabriel RA, Finneran J, Swisher MW, Said ET, Sztain JF, Khatibi B, Wallace AM, Hosseini A, Trescot AM, Ilfeld BM

Background: Acute post-mastectomy pain is frequently challenging to adequately treat with local anesthetic-based regional anesthesia techniques due to its relatively long duration measured in multiple weeks. Case: We report...
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Perioperative duloxetine as part of a multimodal analgesia regime reduces postoperative pain in lumbar canal stenosis surgery: a randomized, triple blind, and placebo-controlled trial

Govil N, Parag K, Arora P, Khandelwal H, Singh A, R

Background: Duloxetine is an antidepressant that is also useful in chronic neuropathic and central origin pain. In this study, the role of duloxetine in decreasing acute postoperative pain after lumbar...
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Barriers and Solutions for Improving Pain Management Practices in Acute Hospital Settings: Perspectives of Healthcare Practitioners for a Pain-Free Hospital Initiative

Akbar N, Teo SP, Hj-Abdul-Rahman HNA, Hj-Husaini HA, Venkatasalu MR

BACKGROUND: Effective pain management is a fundamental human right. However, global disparities in pain management practices exist across health settings. This study explored healthcare practitioners' views on pain management in...
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Intraperitoneal nebulization versus intraperitoneal instillation of ropivacaine for postoperative pain management following laparoscopic donor nephrectomy

Kumar R, Nath SS, Agarwal A

BACKGROUND: Laparoscopic donor nephrectomy is considered less painful than open nephrectomy but is still associated with significant postoperative pain. Studies reported that intraperitoneal instillation of local anesthetics provides uncertain pain...
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Multimodal analgesia with multiple intermittent doses of erector spinae plane block through a catheter after total mastectomy: a retrospective observational study

Hong B, Bang S, Chung W, Yoo S, Chung J, Kim S

BACKGROUND: Although case reports have suggested that the erector spinae plane block (ESPB) may help analgesia for patients after breast surgery, no study to date has assessed its effectiveness. This...
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Low-dose intravenous ketamine versus intravenous ketorolac in pain control in patients with acute renal colic in an emergency setting: a double-blind randomized clinical trial

Sotoodehnia M, Farmahini-Farahani M, Safaie A, Rasooli F, Baratloo A

BACKGROUND: This study was conducted to compare the effectiveness of low-dose ketamine versus ketorolac in pain control in patients with acute renal colic presenting to the emergency department (ED). METHODS: This...
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Comparison of the analgesic efficacy of oxycodone and fentanyl after dental surgery

Lee JE, Park CR, Park SS

BACKGROUND: Oxycodone is a strong m-opioid receptor agonist and has a longer duration of analgesic effect than fentanyl. We compared the use of an intravenous (IV) bolus of oxycodone and...
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Designing the ideal perioperative pain management plan starts with multimodal analgesia

Schwenk ES, Mariano ER

Multimodal analgesia is defined as the use of more than one pharmacological class of analgesic medication targeting different receptors along the pain pathway with the goal of improving analgesia while...
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