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Kahweol from Coffee Induces Apoptosis by Upregulating Activating Transcription Factor 3 in Human Colorectal Cancer Cells

Park GH, Song HM, Jeong JB

Kahweol as a coffee-specific diterpene has been reported to induce apoptosis in human cancer cells. Although some molecular targets for kahweol-mediated apoptosis have been elucidated, the further mechanism for apoptotic...
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Naringenin-Mediated ATF3 Expression Contributes to Apoptosis in Human Colon Cancer

Song HM, Park GH, Eo HJ, Jeong JB

Naringenin (NAR) as one of the flavonoids observed in grapefruit has been reported to exhibit an anti-cancer activity. Activating transcription factor 3 (ATF3) is associated with apoptosis in human colon...
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ATF3 Mediates Anti-Cancer Activity of Trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells

Kim KJ, Lee J, Park Y, Lee SH

Conjugated linoleic acids (CLA) are a family of isomers of linoleic acid. CLA increases growth arrest and apoptosis of human colorectal cancer cells through an isomer-specific manner. ATF3 belongs to...
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The Role of ATF3 Expression and Calcineurin Inhibition in the Putative Cancer Stem Cell Fraction of Human Cutaneous Squamous Cell Carcinoma

Chung BY, Kim BW, Lee MW, Choi JH, Kim CD, Chang SE

  • KMID: 2246267
  • Korean J Dermatol.
  • 2014 Oct;52(10):692-700.
BACKGROUND: A previous study reported that calcineurin inhibition by cyclosporin A (CsA) showed tumor-enhancing effects through the induction of the ATF3 transcription factor and the associated suppression of p53. The...
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Is Activating Transcription Factor 3 Up-Regulated in Patients with Hypospadias?

Gurbuz C, Demir S, Zemheri E, Canat L, Kilic M, Caskurlu T

PURPOSE: Even though hypospadias is one of the most common congenital anomalies, the cause of hypospadias is largely unknown. With regard to molecular biology and microarray technology, it appears that...
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Expression of Activating Transcription Factor 3 in Ischemic Penumbra Region Following Focal Cerebral Ischemia

Song DY, OH KM, Lee JH, Woo RS, Lee YJ, Han JT, Baik TK

  • KMID: 2092940
  • Korean J Anat.
  • 2008 Sep;41(3):173-183.
It has been demonstrated that some of immediate early genes (IEGs) such as c-Jun or fos are induced immediately following neuronal injury and they play an important role in determining...
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