- Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic beta-cells
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Han YE, Lim A, Park SH, Chang S, Lee SH, Ho WK
- KMID: 2160621
- Exp Mol Med.
- 2015 Oct;47(10):e190.
- doi: 10.1038/emm.2015.72
AMP-activated protein kinase (AMPK) is a metabolic sensor activated during metabolic stress and it regulates various enzymes and cellular processes to maintain metabolic homeostasis. We previously reported that activation of... -
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- Molecular and biochemical characterization of a novel actin bundling protein in Acanthamoeba
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Alafag JI, Moon EK, Hong YC, Chung DI, Kong HH
- KMID: 1088765
- Korean J Parasitol.
- 2006 Dec;44(4):331-341.
- doi: 10.3347/kjp.2006.44.4.331
Actin binding proteins play key roles in cell structure and movement particularly as regulators of the assembly, stability and localization of actin filaments in the cytoplasm. In the present study,... -
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- Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet beta cells
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Kalwat MA, Thurmond D
- KMID: 2154256
- Exp Mol Med.
- 2013 Aug;45(8):e37.
The maintenance of whole-body glucose homeostasis is critical for survival, and is controlled by the coordination of multiple organs and endocrine systems. Pancreatic islet beta cells secrete insulin in response... -
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- p53 and DNA-dependent protein kinase catalytic subunit independently function in regulating actin damage-induced tetraploid G1 arrest
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Chae HD, Kim SY, Park SE, Kim J, Shin DY
- KMID: 1245266
- Exp Mol Med.
- 2012 Mar;44(3):236-240.
- doi: 10.3858/emm.2012.44.3.018
We previously reported that the p53 tumor suppressor protein plays an essential role in the induction of tetraploid G1 arrest in response to perturbation of the actin cytoskeleton, termed actin... -
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- Synovial fluid of patients with rheumatoid arthritis induces alpha-smooth muscle actin in human adipose tissue-derived mesenchymal stem cells through a TGF-beta1-dependent mechanism
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Song HY, Kim MY, Kim KH, Lee IH, Shin SH, Lee JS, Kim JH
- KMID: 1104383
- Exp Mol Med.
- 2010 Aug;42(8):565-573.
- doi: 10.3858/emm.2010.42.8.057
Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. Transforming growth factor-beta1 (TGF-beta1) is a secreted protein that promotes differentiation of... -
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- Endothelial F-actin changes in the alkali burned rabbit cornea
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Kim EK, Kim HB, Chung YT, Kim IC
- KMID: 1125987
- Yonsei Med J.
- 1994 Dec;35(4):484-492.
- doi: 10.3349/ymj.1994.35.4.484
The healing mechanism of corneal endothelium after alkali burn was not completely understood. Rabbit cornea was burned with 1N sodium hydxoside for 1 minute. Endothelial F-actin was stained with NBD-phallacidin... -
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- beta PAK-interacting exchange factor may regulate actin cytoskeleton through interaction with actin
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Lee CS, Kim KY, Im JB, Choi JW, Kim HK, Park JS, Shin EY, Kim SR, Kim EG
- KMID: 1103327
- Exp Mol Med.
- 2004 Dec;36(6):582-587.
p21-activated kinase (PAK)-interacting exchange factor (PIX) is known to be involved in regulation of Cdc42/Rac GTPases and PAK activity. PIX binds to the proline-rich region of PAK, and regulates biological... -
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