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Prevalence and Risk Factors for Low Back Pain in 1,355 Young Adults: A Cross-Sectional Study

Ganesan S, Acharya AS, Chauhan R, Acharya S

STUDY DESIGN: Cross-sectional study. PURPOSE: To evaluate the prevalence and various risk factors for low back pain (LBP) in young adults in India. OVERVIEW OF LITERATURE: LBP is an emerging problem in...
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Sacral Insufficiency Fractures Mimicking Lumbar Spine Pathology

Sudhir G, K L K, Acharya S, Chahal R

Sacral insufficiency fractures (SIFs) are a common cause of back pain in the elderly. SIFs mimic the symptoms of lumbar spine pathology and so are commonly missed or underdiagnosed. Here...
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Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors

Min C, Zhang X, Zheng M, Sun N, Acharya S, Zhang X, Kim KM

Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which...
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Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors

Paudel S, Kim E, Zhu A, Acharya S, Min X, Cheon SH, Kim KM

In this study, we determined the effect of 24 different synthetic 4-benzylpiperidine carboxamides on the reuptake of serotonin, norepinephrine, and dopamine (DA), and characterized their structure–activity relationship. The compounds with...
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Catalpol and Mannitol, Two Components of Rehmannia glutinosa, Exhibit Anticonvulsant Effects Probably via GABA A Receptor Regulation

Kim M, Acharya S, Botanas CJ, Custodio RJ, Lee HJ, Sayson LV, Abiero A, Lee YS, Cheong JH, Kim Km, Kim HJ

Epilepsy is a brain disorder that affects millions of people worldwide and is usually managed using currently available antiepileptic drugs, which result in adverse effects and are ineffective in approximately...
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Clinicoradiological Risk Factors Associated with Inability to Achieve Minimum Clinically Important Difference in Operated Cases of Cervical Spondylotic Myelopathy

Acharya S, Khanna V, Chahal RS, Kalra KL, Vishwakarma G

Study Design: This is a retrospective cohort study. Purpose: This study aimed to identify the clinicoradiological risk factors associated with the inability to achieve minimum clinically important difference (MCID) on the...
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Prevalence of Hepatitis B Virus (HBV) Among Blood Donors in Eastern Saudi Arabia: Results From a Five-Year Retrospective Study of HBV Seromarkers

Alzahrani , Muzaheed , Shaikh SS, Alomar AI, Acharya S, Elhadi N

BACKGROUND: Transfusion-transmissible hepatitis B virus (HBV) infection is a major problem worldwide. Recently, confirmatory nucleic acid tests (NATs) for HBV DNA have been employed in several countries. We assessed the...
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Stem Cell Therapy for Avascular Necrosis of Femoral Head in Sickle Cell Disease: Report of 11 Cases and Review of Literature

Sadat-Ali , Azam MQ, Elshabouri EM, Tantawy AM, Acharya S

BACKGROUND AND OBJECTIVE: Sickle cell disease (SCD) is quite common in eastern Saudi Arabia and Avascular necrosis of femoral head (ANFH) occurs in 30% of the young patients leading to...
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Risk Factors for Preterm Birth and Low Birth Weight Among Pregnant Indian Women: A Hospital-based Prospective Study

Tellapragada C, Eshwara VK, Bhat P, Acharya S, Kamath A, Bhat S, Rao C, Nayak S, Mukhopadhyay C

OBJECTIVES: The present study was undertaken to study the maternal risk factors for preterm birth (PTB) and low birth weight (LBW) with a special emphasis on assessing the proportions of...
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