- Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells
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Lee HI, Cho HJ, Han JA, Jang SY, Wang KM, Kang HT, Hwang ES
- KMID: 1052947
- Exp Mol Med.
- 2008 Apr;40(2):246-253.
- doi: 10.3858/emm.2008.40.2.246
Nicotinamide at millimolar concentrations affects cell survival in various conditions, and is being utilized therapeutically in many human diseases. However, the effect of an acute treatment of nicotinamide at such... -
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- Synapsin-1 and tau reciprocal O-GlcNAcylation and phosphorylation sites in mouse brain synaptosomes
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Kang MJ, Kim C, Jeong H, Cho BK, Ryou AL, Hwang D, Mook-Jung , Yi EC
- KMID: 2154248
- Exp Mol Med.
- 2013 Jun;45(6):e29.
O-linked N-acetylglucosamine (O-GlcNAc) represents a key regulatory post-translational modification (PTM) that is reversible and often reciprocal with phosphorylation of serine and threonine at the same or nearby residues. Although recent... -
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