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Peripheral blood immune cell-based biomarkers in anti-PD-1/PD-L1 therapy

Kim KH, Kim CG, Shin EC

Immune checkpoint blockade targeting PD-1 and PD-L1 has resulted in unprecedented clinical benefit for cancer patients. Anti-PD-1/PD-L1 therapy has become the standard treatment for diverse cancer types as monotherapy or...
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Metallic Artifacts on MR Imaging and Methods for Their Reduction

Choo HJ, Lee SJ, Lee YH

Metallic artifacts on MR imaging are typically induced by differences in magnetic susceptibility between the metallic implant and surrounding tissue. Conventional techniques for metal artifact reduction require MR machines with...
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Feasibility of Simultaneous Multislice Acceleration Technique in Diffusion-Weighted Magnetic Resonance Imaging of the Rectum

Park JH, Seo N, Lim JS, Hahm J, Kim MJ

OBJECTIVE: To assess the feasibility of simultaneous multislice-accelerated diffusion-weighted imaging (SMS-DWI) of the rectum in comparison with conventional DWI (C-DWI) in rectal cancer patients. MATERIALS AND METHODS: This study included 65...
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Methylphenidate and Central Precocious Puberty: A Probable Side Effect among Seven Children with the Attention Deficit Hyperactivity Disorder

Ergür AT, Gül H, Gül A

Methylphenidate (MPH) is the most preferred drug for treatment of the attention deficit hyperactivity disorder (ADHD). Here, we aimed to discuss the possible effects and mechanisms of MPH on precocious...
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Prognostic value of right pulmonary artery distensibility in dogs with pulmonary hypertension

Chan IP, Weng MC, Hsueh T, Lin YC, Lin SL

The right pulmonary artery distensibility (RPAD) index has been used in dogs with pulmonary hypertension (PH) caused by heartworm infection, myxomatous mitral valve disease, or patent ductus arteriosus. We hypothesized...
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High-Resolution Magnetic Resonance Imaging Using Compressed Sensing for Intracranial and Extracranial Arteries: Comparison with Conventional Parallel Imaging

Suh CH, Jung SC, Lee HB, Cho SJ

OBJECTIVE: To compare conventional sensitivity encoding (SENSE) to compressed sensing plus SENSE (CS) for high-resolution magnetic resonance imaging (HR-MRI) of intracranial and extracranial arteries. MATERIALS AND METHODS: HR-MRI was performed in...
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High Acceleration Three-Dimensional T1-Weighted Dual Echo Dixon Hepatobiliary Phase Imaging Using Compressed Sensing-Sensitivity Encoding: Comparison of Image Quality and Solid Lesion Detectability with the Standard T1-Weighted Sequence

Nam JG, Lee JM, Lee SM, Kang HJ, Lee ES, Hur BY, Yoon JH, Kim E, Doneva M

OBJECTIVE: To compare a high acceleration three-dimensional (3D) T1-weighted gradient-recalled-echo (GRE) sequence using the combined compressed sensing (CS)-sensitivity encoding (SENSE) method with a conventional 3D GRE sequence using SENSE, with...
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Accelerated Time-of-Flight Magnetic Resonance Angiography with Sparse Undersampling and Iterative Reconstruction for the Evaluation of Intracranial Arteries

Tang H, Hu N, Yuan Y, Xia C, Liu X, Zuo P, Stalder AF, Schmidt M, Zhou X, Song B, Sun J

OBJECTIVE: To compare the image quality of three-dimensional time-of-flight (TOF) magnetic resonance angiography (MRA) with sparse undersampling and iterative reconstruction (sparse TOF) with that of conventional TOF MRA. MATERIALS AND METHODS:...
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Can Cupulolithiasis Affect the Time Constant or Gain of the Velocity Step Test?

Kim MT, Choi JE, Lee MY, Jung JY

OBJECTIVES: The nystagmus evoked by an angular velocity step is influenced by the cupula dynamics and the status of velocity storage mechanisms. This study questioned whether the cupulolithiasis of horizontal...
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Implication of Porphyromonas gingivalis in colitis and homeostasis of intestinal epithelium

Seo Y, Oh SJ, Ahn JS, Shin YY, Yang JW, Kim HS

Emerging evidences have reported that periodontitis can be a risk factor for the pathogenesis of various systemic diseases. Porphyromonas gingivalis (Pg), one of the crucial pathogens in chronic periodontitis, has...
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Development of a Novel Intraoperative Neuromonitoring System Using an Accelerometer Sensor in Thyroid Surgery: A Porcine Model Study

Sung ES, Lee JC, Shin SC, Kwon HK, Na HS, Park DH, Choi SW, Ro JH, Lee BJ

OBJECTIVES: The sensitivity and positive predictive value of widely used intraoperative neuromonitoring (IONM) using electromyography (EMG) of the vocalis muscle in thyroid surgery are controversial. Thus, we developed a novel...
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Real-Time Computed Tomography Volume Visualization with Ambient Occlusion of Hand-Drawn Transfer Function Using Local Vicinity Statistic

Kim J, Ha T, Kye H

OBJECTIVES: In this paper, we present an efficient method to visualize computed tomography (CT) datasets using ambient occlusion, which is a global illumination technique that adds depth cues to the...
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Response Patterns of Nursing Unit Managers regarding Workplace Bullying: A Q Methodology Approach

Choi JK, Lee B

PURPOSE: The purpose of this study was to identify the response patterns of nursing unit managers regarding workplace bullying. METHODS: Q methodology was used to identify the response patterns. Thirty-six Q...
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Growth Hormone and Aging: Updated Review

Bartke A

Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, and experimental studies. The age-related decline in GH levels is variously interpreted as a symptom of...
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Exogenous spermidine ameliorates tubular necrosis during cisplatin nephrotoxicity

Yoon SP, Kim J

The hallmark of cisplatin-induced acute kidney injury is the necrotic cell death in the kidney proximal tubules. However, an effective approach to limit cisplatin nephrotoxicity remains unknown. Spermidine is a...
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CD57 (Leu-7, HNK-1) immunoreactivity seen in thin arteries in the human fetal lung

Ishizuka S, Jin ZW, Yamamoto M, Murakami G, Takayama T, Hayashi K, Abe SI

CD57 (synonyms: Leu-7, HNK-1) is a well-known marker of nerve elements including the conductive system of the heart, as well as natural killer cells. In lung specimens from 12 human...
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The Clinical Efficacy of Vestibular Function Tests in Patients with Acute Unilateral Vestibulopathy

Kang BH, Kim JI

OBJECTIVES: Aim of this study is to investigate the clinical efficacy of the vestibular function tests (VFTs) and the predictability of lesion side of vestibular asymmetry parameters in acute unilateral...
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Effect of Structured Bed Exercise on Uterine Contractions, Fetal Heart Rate Patterns, and Maternal Psychophysical Symptoms of Hospitalized High-Risk Pregnant Women: A Randomized Control Trial

Kim YJ, Park YJ

PURPOSE: This study examined the effect on uterine contraction frequency (UCF), blood pressure (BP), heart rate (HR), fetal heart rate (FHR) patterns and psychophysical symptoms (physical discomfort, anxiety, and depression)...
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Optimization of the Flip Angle and Scan Timing in Hepatobiliary Phase Imaging Using T1-Weighted, CAIPIRINHA GRE Imaging

Kim J, Kim BS, Lee JS, Woo ST, Choi GM, Kim SH, Lee HK, Lee MS, Lee KR, Park JH

PURPOSE: This study was designed to optimize the flip angle (FA) and scan timing of the hepatobiliary phase (HBP) using the 3D T1-weighted, gradient-echo (GRE) imaging with controlled aliasing in...
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The adiposity rebound in the 21st century children: meaning for what?

Kang MJ

With the increase in the prevalence of overweight and obesity worldwide, early adiposity rebound, which is known to have a strong association with obesity, has recently been a focus of...
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