- Aberrant Crypt Foci: Histopathologic Classification and Profiles of Mucin Secretion
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Kim A, Choi JS, Choi WJ, Moon HY
- KMID: 2037272
- Korean J Pathol.
- 2000 Jan;34(1):50-55.
Aberrant crypt foci (ACF) are grossly unidentifiable lesions of the colon and visible only with low-power microscopic examinations after methylene blue stain. To establish the role of ACF in colorectal... -
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- Aberrant Crypt Foci in the Background Mucosa of Colorectal Adenocarcinoma
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Kim DH, Hong EK
- KMID: 2166231
- Cancer Res Treat.
- 2001 Jun;33(3):216-224.
PURPOSE: This study was performed in order to determine the histologic features, incidence & frequency of the Aberrant Crypt Foci (ACFs) including mucosal abnormalities arising in the sporadic colonic cancer. MATERIALS... -
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- Sequential Changes in Aberrant Crypt Foci and Lectin Expression in the Early and Late Stages of DMH-Induced Colon Carcinogenesis in Rats
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Won HS, Maeng LS, Chae HS, Kim HK, Cho YS, Kang JH, Jang HS, Ryu MR
- KMID: 2284269
- Gut Liver.
- 2012 Apr;6(2):229-234.
BACKGROUND/AIMS: The purpose of this study was to investigate the malignant potential of aberrant crypt foci (ACF) by measuring the multiplicity of crypts and lectin expression in the early and... -
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- Topographic, histological and molecular study of aberrant crypt foci identified in human colon in different clinical groups
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Ghosh S, Gupta B, Verma P, Vishnubathla S, Pal S, Dash NR, Gupta SD, Das P
- KMID: 2402655
- Intest Res.
- 2018 Jan;16(1):116-125.
- doi: 10.5217/ir.2018.16.1.116
BACKGROUND/AIMS: Aberrant crypt foci (ACF) are early microscopic lesions of the colonic mucosa, which can be detected by magnified chromoendoscopy. Herein, we have investigated whether ACF identified in different clinical... -
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- Dose-response assessment of the anti-cancer efficacy of soy isoflavones in dimethylhydrazine-treated rats fed 6% fructooligosaccharide
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Sung HY, Choi YS
- KMID: 2313350
- Nutr Res Pract.
- 2008 Jun;2(2):55-61.
We investigated the combinatorial effects of different doses of dietary soy isoflavones (SI) and fructooligosaccharide (FOS) in a rat model of colon cancer. We hypothesized that increased bioavailability of SI... -
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- Dietary zinc inhibits the formation of colonic preneoplastic lesion induced by azoxymethane and dextran sodium sulfate in mice
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Park H, Kim DY, Kang BS, Yoon JS, Jeong JH, Nam SY, Yun YW, Kim JS, Lee BJ
- KMID: 1435822
- Korean J Vet Res.
- 2012 Jun;52(2):115-124.
Colorectal cancer (CRC) is one of the leading causes of cancer death in western countries or in the developed countries. Zinc intake has been associated with decreased risk of CRC.... -
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- Suppressive Effect of Zinc on the Formation of Colonic Preneoplastic Lesions in the Mouse Fed High Levels of Dietary Iron
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Park H, Kang BS, Kim DY, Yoon JS, Jeong JH, Nam SY, Yun YW, Kim JS, Lee BJ
- KMID: 2052550
- Toxicol Res.
- 2012 Mar;28(1):39-49.
We investigated the effect of zinc on the formation of colonic aberrant crypt foci induced by azoxymethane (AOM) followed by dextran sodium sulfate (DSS) in mice with high iron diet... -
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- Effect of iron overload with ascorbic acid on experimental colon carcinogenesis in mice
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Ahn TH, Kim SJ, Jeong JH, Nam SY, Yun YW, Lee BJ
- KMID: 2405357
- J Biomed Transl Res.
- 2017 Dec;18(4):136-141.
- doi: 10.12729/jbtr.2017.18.4.136
Excessive iron can promote the production of free radicals, thereby leading to harmful effects on cancer and aging. Ascorbic acid is not only an antioxidant but also a co-factor of... -
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- Loss of DNA-dependent Protein Kinase Catalytic Subunit (DNA- PKcs) Expression in Gastric Cancers
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Lee HS, Yang HK, Kim WH, Choe G
- KMID: 1571464
- Cancer Res Treat.
- 2005 Apr;37(2):98-102.
PURPOSE: DNA-PKcs is one of the DNA repair genes. It was recently found that hyperplasia and dysplasia of the intestinal mucosa and the production of aberrant crypt foci were developed... -
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- Chemopreventive effect of alpha-viniferin in azoxymethane-induced mouse colorectal tumor and Caco-2 cells
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Kwak DH, Shin SK, Youm SY, Kim TW, Kim Y, Ahn B
- KMID: 2286283
- J Biomed Res.
- 2015 Jun;16(2):60-66.
- doi: 10.12729/jbr.2015.16.2.060
alpha-Viniferin (AVF), a trimer of resveratrol, is known to have an anti-inflammatory effect via inhibition of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). It has been reported that up-regulated... -
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