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Efficacy and safety of abrilumab, an α4β7 integrin inhibitor, in Japanese patients with moderate-to-severe ulcerative colitis: a phase II study

Hibi T, Motoya S, Ashida T, Sai S, Sameshima , Nakamura S, Maemoto A, Nii M, Sullivan B, Gasser Jr , Suzuki Y

BACKGROUND/AIMS: Inhibition of α4β7 integrin has been shown to be effective for induction and maintenance therapy in patients with ulcerative colitis (UC). We investigated the effects of varying doses of...
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Alteration of Ionic Zinc Distribution in Rat Spinal Ganglion by Inflammatory Pain Stimulus: Autometallography

Lee B, Jun G, Kim YS, Lee B, Lee YI, Kim DJ, Jo SM

  • KMID: 2224492
  • Korean J Anat.
  • 2005 Dec;38(6):561-566.
This study was designed to investigate any correlation between the mechanism of pain development and changes of histochemically reactive zinc contents in the rat spinal ganglion following complete Freund's Adjuvant...
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Decrease in Zinc Concentration in the Rat Spinal Gray Matter Induced by Peripheral Nerve Ligation, and its Relations with Increased Pain Threshold

Kim SJ, Choi YH, Yu YC, Lee B, Jo SM

  • KMID: 2224499
  • Korean J Anat.
  • 2004 Aug;37(4):369-375.
This study was designed to investigate any correlation between the mechanism of pain development and changes of histochemically-reactive zinc contents in the rat spinal cords following peripheal nerve ligation. Male...
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Protection Effects of the Adrenalectomy on the Neuronal Death following Kainc Acid in the Rat Hippocampus

Kim YK, Shin HS, Kim DJ, Jo SM

  • KMID: 2092780
  • Korean J Anat.
  • 2001 Oct;34(5):509-516.
Chelatable zinc ions from synaptic vesicles have been shown to contribute to neuronal death caused by stroke, epilepsy and head trauma. Elevated glucocorticoid concentration exacerbates such neuron loss, while low...
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The Effect of Amniotic Membrane Gra ft on the Inhibition of Corneal Haze in Rabbit

Woo HM, Kim MS, Kweon OK

  • KMID: 2205550
  • J Korean Ophthalmol Soc.
  • 1999 Sep;40(9):2385-2394.
This study was performed to investigate histopathologically the effect of amniotic membrane graft (AMG)on haze in deep stromal wound of cornea. The excimer laser phototherapeutic keratectomy (PTK)was used to create...
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