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A Case of Dihydropteridine Reductase Deficiency

Oh SJ, Hong YH, Lee YW, Lee ST, Ki CS, Lee DH

  • KMID: 1473822
  • J Genet Med.
  • 2009 Dec;6(2):170-174.
Tetrahydrobiopterin (BH4) deficiency is caused by mutations in genes encoding enzymes involved in the synthesis and regeneration of BH4. The condition is usually accompanied by hyperphenylalaninemia (HPA) and deficiency of...
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Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems

Hong KB, Park Y, Suh HJ

BACKGROUND/OBJECTIVES: The aim of this study was to evaluate the biological and sleep-promoting effects of combined γ-aminobutyric acid (GABA) and 5-hydroxytryptophan (5-HTP) using caffeine-induced sleepless fruit flies, ICR mice, and...
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Immuno-electronmicroscopic study on the serotoninergic taste cells and calcitonin gene-related peptide nerve fibers in mouse taste buds

Kim DJ

  • KMID: 2224575
  • Korean J Anat.
  • 1999 Apr;32(2):143-152.
To investigate the distribution, ultrastructure and synapsis of serotoninergic cells and CGRP nerve fibers in mammalian taste buds, immunohistochemistry and electronmicroscopy were applied to mice vallate papillae. In normal mice,...
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An Autoradiographic Study on Metabolism of Serotonin in Cerebral Nerve Cells Using 5-Hydroxytryptophan-C

Choi KD, Ahn SB, Oh YK, Rhim KS, Moon BY

In order to demonstrate autoradiographically the sites of serotonin metabolism in the brain, DL 5-HTP and DL 5-HTP-C14 were intraperitoneally administered to healthy adult mice. In order to distinguish histochemically...
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5-hydroxy-L-tryptophan Suppressed Food Intake in Rats Despite an Increase in the Arcuate NPY Expression

Moon YW, Choi SH, Yoo SB, Lee JH, Jahng JW

This study was conducted to define the underlying mechanism of hypophagia induced by increased central serotonergic action. Rats received 3 daily injections of 5-hydroxy-L-tryptophan (5-HTP), a serotonin precursor, at a...
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