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LIN28B confers radio-resistance through the posttranscriptional control of KRAS

Jeong SH, Wu HG, Park WY

To screen the differentially expressed microRNAs related to radio-resistance, we compared the microRNA profiles of lung cancer cells with different responses to ionizing radiation (IR). Of 328 microRNAs in microarray,...
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Knockdown of 14-3-3zeta enhances radiosensitivity and radio-induced apoptosis in CD133+ liver cancer stem cells

Lee YK, Hur W, Lee SW, Hong SW, Kim SW, Choi JE, Yoon SK

14-3-3zeta is related to many cancer survival cellular processes. In a previous study, we showed that silencing 14-3-3zeta decreases the resistance of hepatocellular carcinoma (HCC) to chemotherapy. In this study,...
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