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Activation of B cells using Schneider 2 cells expressing CD40 ligand for the enhancement of antigen presentation in vitro

Yoon SH, Cho HI, Kim TG

  • KMID: 1116202
  • Exp Mol Med.
  • 2005 Dec;37(6):567-574.
CD40 ligand (CD40L) expressed by activated CD4+ T cells is a family member of membrane bound TNF family ligand and its interaction with CD40 expressed in APC has been shown...
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Requirements for in vitro growth of human thymocytes

Park SH, Bae YM, Park WS, Kim TJ, Chung DH, Song HG, Cho BJ, Kim CW, Lee SK

Since it is difficult to study human thymocyte maturation in vitro, we have developed an in vitro thymocyte culture system which has allowed us to select the optimal growth conditions...
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In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1

La S, Kim E, Kwon B

  • KMID: 1056231
  • Exp Mol Med.
  • 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive...
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Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10

Yang SH, Park MJ, Yoon IH, Kim SY, Hong SH, Shin JY, Nam HY, Kim YH, Kim B, Park CG

Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on...
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