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Infarct Size-limiting Effect of Calcium Preconditioning in Rabbit Hearts

Kim HD

Recent studies demonstrated that brief period of Ca2+ depletion and repletion (Ca2+ preconditioning, CPC) has strong protective effects against ischemia in a rat heart. CPC and classic preconditioning (IPC) were...
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Representational difference analysis of cDNA identifies novel genes expressed following preconditioning of the heart

Fauchon MA, Pell TJ, Baxter GF, Yellon DM, Latchman D, Hubank MF, Mayn LV

  • KMID: 1093466
  • Exp Mol Med.
  • 2005 Aug;37(4):311-322.
Preconditioning of the myocardium rapidly induces a number of transcription factors, which are likely to be responsible for a cascade of transcriptional changes underlying the development of delayed adaptation. Identifying...
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Activation of Akt/protein kinase B mediates the protective effects of mechanical stretching against myocardial ischemia-reperfusion injury

Kim CH, Hao J, Ahn HY, Kim SW

Akt/protein kinase B is a well-known cell survival factor and activated by many stimuli including mechanical stretching. Therefore, we evaluated the cardioprotective effect of a brief mechanical stretching of rat...
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