- Extracellular HIV-1 Tat up-regulates expression of matrix metalloproteinase-9 via a MAPK-NF-kappaB dependent pathway in human astrocytes
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Ju SM, Song HY, Lee JA, Lee SJ, Choi SY, Park J
- KMID: 1109431
- Exp Mol Med.
- 2009 Feb;41(2):86-93.
- doi: 10.3858/emm.2009.41.2.011
The infiltration of monocytes into the CNS represents one of the early steps to inflammatory events in AIDS-related encephalitis and dementia. Increased activity of selected matrix metalloproteinases (MMPs) such as... -
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- Extracellular HIV-1 Tat enhances monocyte adhesion by up-regulation of ICAM-1 and VCAM-1 gene expression via ROS-dependent NF-kappaB activation in astrocytes
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Song HY, Ryu J, Ju SM, Park LJ, Lee JA, Choi SY, Park J
- KMID: 1103678
- Exp Mol Med.
- 2007 Feb;39(1):27-37.
One of characteristic features of AIDS-related encephalitis and dementia is the infiltration of monocytes into the CNS. HIV-1 Tat was demonstrated to facilitate monocyte entry into the CNS. In this... -
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