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Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma

Gulley ML

A small set of gastric adenocarcinomas (9%) harbor Epstein-Barr virus (EBV) DNA within malignant cells, and the virus is not an innocent bystander but rather is intimately linked to pathogenesis...
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Comparison of Functional Gene Annotation of Toxascaris leonina and Toxocara canis using CLC Genomics Workbench

Kim KU, Park SK, Kang SA, Park MK, Cho MK, Jung HJ, Kim KY, Yu HS

  • KMID: 1792143
  • Korean J Parasitol.
  • 2013 Oct;51(5):525-530.
The ascarids, Toxocara canis and Toxascaris leonina, are probably the most common gastrointestinal helminths encountered in dogs. In order to understand biological differences of 2 ascarids, we analyzed gene expression...
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The Path to Clinical Proteomics Research: Integration of Proteomics, Genomics, Clinical Laboratory and Regulatory Science

Boja ES, Rodriguez

Better biomarkers are urgently needed to cancer detection, diagnosis, and prognosis. While the genomics community is making significant advances in understanding the molecular basis of disease, proteomics will delineate the...
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Perspective beyond Cancer Genomics: Bioenergetics of Cancer Stem Cells

Ishii H, Doki Y, Mori M

Although the notion that cancer is a disease caused by genetic and epigenetic alterations is now widely accepted, perhaps more emphasis has been given to the fact that cancer is...
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Integrative epigenomic and genomic analysis of malignant pheochromocytoma

Sandgren J, Andersson , Rada-Iglesias A, Enroth S, Akerstrom , Dumanski J, Komorowski J, Westin G, Wadelius C

Epigenomic and genomic changes affect gene expression and contribute to tumor development. The histone modifications trimethylated histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) are epigenetic regulators associated to...
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RNA Interference in Functional Genomics and Medicine

Kim VN

RNA interference (RNAi) is the sequence-specific gene silencing induced by double-stranded RNA (dsRNA). Being a highly specific and efficient knockdown technique, RNAi not only provides a powerful tool for functional...
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