- Therapeutic effect of hepatocyte growth factor-secreting mesenchymal stem cells in a rat model of liver fibrosis
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Kim MD, Kim SS, Cha HY, Jang SH, Chang DY, Kim W, Suh-Kim H, Lee JH
- KMID: 2155375
- Exp Mol Med.
- 2014 Aug;46(8):e110.
- doi: 10.1038/emm.2014.49
Bone marrow-derived mesenchymal stromal cells (MSCs) have been reported to be beneficial for the treatment of liver fibrosis. Here, we investigated the use of genetically engineered MSCs that overexpress hepatocyte... -
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- Antitumor immunity induced by tumor cells engineered to express a membrane-bound form of IL-2
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Chang MR, Lee WH, Choi JW, Park SO, Paik SG, Kim YS
- KMID: 1056237
- Exp Mol Med.
- 2005 Jun;37(3):240-249.
Transduction of cytokine gene into tumor cells is a promising method of tumor therapy, but the value is limited by accompanying side effects. To focus antitumor immune response to tumor... -
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