- Targeting efficiency of a-1,3-galactosyl transferase gene in pig fetal fibroblast cells
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Jin DI, Lee SH, Choi JH, Lee JS, Lee JE, Park KW, Seo JS
- KMID: 1119341
- Exp Mol Med.
- 2003 Dec;35(6):572-577.
Animal cloning technology with somatic cells provides an alternative tool to conventional methods for producing transgenic animals. Gene targeting in animals is made feasible using somatic cells with homologous recombination... -
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- Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2
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Yun HJ, Cho YH, Moon Y, Park YW, Yoon HK, Kim YJ, Cho SH, Lee YI, Kang BS, Kim WJ, Park K, Seo W
- KMID: 756337
- Exp Mol Med.
- 2008 Jun;40(3):345-353.
- doi: 10.3858/emm.2008.40.3.345
For cancer gene therapy, cancer-specific over-expression of a therapeutic gene is required to reduce side effects derived from expression of the gene in normal cells. To develop such an expression... -
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