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Frequent Epigenetic Inactivation of XAF1 by Promotor Hypermethylation in Human Colon Cancers

Jang JY, Kim HJ, Chi SG, Lee KY, Nam KD, Kim NH, Lee SK, Joo KR, Dong SH, Kim BH, Chang YW, Lee JI, Chang R

  • KMID: 772766
  • Korean J Gastroenterol.
  • 2005 Apr;45(4):285-293.
BACKGROUND/AIMS: X-linked inhibitor of apoptosis (XIAP) is the most potent member of the IAP family that exerts antiapoptotic effects. Recently, XIAP-associated factor 1 (XAF1) and two mitochondrial proteins, Smac/DIABLO...
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Downregulation of regenerating islet-derived 3 alpha (REG3A) in primary human gastric adenocarcinomas

Choi B, Suh Y, Kim WH, Christa L, Park J, Bae CD

  • KMID: 1091074
  • Exp Mol Med.
  • 2007 Dec;39(6):796-804.
Gastric carcinoma is considered to be one of the most prevalent cancers worldwide. We have performed differential-display polymerase chain reaction (DD-PCR) in order to compare the gene expression profile of...
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Inactivation patterns of p16/INK4A in oral squamous cell carcinomas

Lee JK, Kim MJ, Hong SP, Hong SD

  • KMID: 1380211
  • Exp Mol Med.
  • 2004 Apr;36(2):165-171.
The p16/INK4A is one of the major target genes in carcinogenesis and its inactivation has frequently been reported in other types of tumors. The purpose of this study is to...
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