- Gene-Environment Interactions in Asthma: Genetic and Epigenetic Effects
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Lee JU, Kim JD, Park CS
- KMID: 2366325
- Yonsei Med J.
- 2015 Jul;56(4):877-886.
- doi: 10.3349/ymj.2015.56.4.877
Over the past three decades, a large number of genetic studies have been aimed at finding genetic variants associated with the risk of asthma, applying various genetic and genomic approaches... -
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- Update on Early Nutrition and Food Allergy in Children
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Lee SE, Kim H
- KMID: 2374070
- Yonsei Med J.
- 2016 May;57(3):542-548.
- doi: 10.3349/ymj.2016.57.3.542
With growing evidence of an increase in the prevalence, food allergy has been emerged as a new public health problem. As treatment and management of food allergy remain challenging, more... -
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- Epigenetic modulation as a therapeutic approach for pulmonary arterial hypertension
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Kim JD, Lee A, Choi J, Park Y, Kang H, Chang W, Lee MS, Kim J
- KMID: 2155429
- Exp Mol Med.
- 2015 Jul;47(7):e175.
- doi: 10.1038/emm.2015.45
Pulmonary arterial hypertension (PAH) is a rare but progressive and currently incurable disease, which is characterized by vascular remodeling in association with muscularization of the arterioles, medial thickening and plexiform... -
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- Integrative epigenomic and genomic analysis of malignant pheochromocytoma
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Sandgren J, Andersson , Rada-Iglesias A, Enroth S, Akerstrom , Dumanski J, Komorowski J, Westin G, Wadelius C
- KMID: 1104209
- Exp Mol Med.
- 2010 Jul;42(7):484-502.
- doi: 10.3858/emm.2010.42.7.050
Epigenomic and genomic changes affect gene expression and contribute to tumor development. The histone modifications trimethylated histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) are epigenetic regulators associated to... -
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