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Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells

Park HY, Jeon YK, Shin HJ, Kim IJ, Kang HC, Jeong SJ, Chung DH, Lee CW

  • KMID: 1094660
  • Exp Mol Med.
  • 2007 Apr;39(2):195-204.
The BubR1 mitotic-checkpoint protein monitors proper attachment of microtubules to kinetochores, and links regulation of chromosome-spindle attachment to mitotic-checkpoint signaling. Thus, disruption of BubR1 activity results in a loss of...
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