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Overexpression of SOX9 in mouse embryonic stem cells directs the immediate chondrogenic commitment

Kim JH, Do HJ, Yang HM, Oh JH, Choi SJ, Kim DK, Cha KY, Chung HM

  • KMID: 1093460
  • Exp Mol Med.
  • 2005 Aug;37(4):261-268.
Mouse embryonic stem (mES) cells are capable of undergoing chondrogenesis in vitro. To enhance this process, the human SOX9 (hSOX9) cDNA was delivered into mES cells and the clones overexpressing...
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Comparison of Phenotypic Characterization between "Alginate Bead" and "Pellet" Culture Systems as Chondrogenic Differentiation Models for Human Mesenchymal Stem Cells

Yang IH, Kim SH, Kim YH, Sun HJ, Kim SJ, Lee JW

Chondrogenesis involves the recruitment of mesenchymal cells to differentiate into chondroblasts, and also the cells must synthesize a cartilage-specific extracellular matrix. There were two representative culture systems that promoted the...
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