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TGF-beta1-induced PINCH-1-ILK-alpha-parvin complex formation regulates mesangial cell proliferation and hypertrophy

Kim SM, Kim N, Lee S, Kim DK, Lee YM, Ahn SH, Song JH, Choi BK, Wu C, Jung KY

  • KMID: 756075
  • Exp Mol Med.
  • 2007 Aug;39(4):514-523.
TGF-beta1-induced glomerular mesangial cell (GMC) injury is a prominent characteristic of renal pathology in several kidney diseases, and a ternary protein complex consisting of PINCH-1, integrin-linked kinase (ILK) and alpha-parvin...
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