- Proposed Motor Scoring System in a Porcine Model of Parkinson's Disease induced by Chronic Subcutaneous Injection of MPTP
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Moon JH, Kim JH, Im HJ, Lee DS, Park EJ, Song K, Oh HJ, Hyun SB, Kang SC, Kim H, Moon HE, Park HW, Lee HJ, Kim EJ, Kim S, Lee BC, Paek SH
- KMID: 2165531
- Exp Neurobiol.
- 2014 Sep;23(3):258-265.
- doi: 10.5607/en.2014.23.3.258
Destruction of dopaminergic neurons in the substantia nigra pars compacta (SNpc) is a common pathophysiology of Parkinson's disease (PD). Characteristics of PD patients include bradykinesia, muscle rigidity, tremor at rest... -
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- Comparison and Analysis for CT Findings of Gastric Adenocarcinoma and Gastric Lymphoma
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Kim MY, Kim YS, Kim HK, Kim YT, Moon HE, Han ST
- KMID: 2102384
- J Korean Radiol Soc.
- 1994 Sep;31(3):489-494.
PURPOSE: The purpose of this study is to analyze and compare the CT findings of gastric adenocarcmoma and gastric lymphoma. MATERIALS AND METHODS: We retrospectively analyzed and compared the CT findings in... -
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- Operated DeBakey Type III Dissecting Aortic Aneurysm: Review of 12 cases
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Kim HK, Moon HE, Han CY, Lee GJ, Oh SJ, Yoon SR, Shim JC
- KMID: 2102561
- J Korean Radiol Soc.
- 1995 Jun;32(6):875-882.
PURPOSE: We evaluated the indications of operation and radiologic findings in 12 operated DeBakey type III aortic dissections. MATERIAL AND METHODS: We retrospectively reviewed radiologic findings of 12 operated DeBakey type III aortic... -
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- Postoperative CT Findings of Aortic Aneurysm and Dissection
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Kim MY, Kim HK, Moon HE, Lee GJ, Shim JC, Seong SO, Lee HS, Hah CY
- KMID: 1831117
- J Korean Radiol Soc.
- 1995 Nov;33(5):717-724.
PURPOSE: To assess the postoperative CT findings of aortic aneurysms or dissections treared by resection- and-graft replacement or continuous-suture graft-inclusion technique MATERIALS AND METHODS: We reviewed postoperative follow-up CT findings of 14... -
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- The Unreliability of MTT Assay in the Cytotoxic Test of Primary Cultured Glioblastoma Cells
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Jo HY, Kim Y, Park HW, Moon HE, Bae S, Kim J, Kim DG, Paek SH
- KMID: 2165560
- Exp Neurobiol.
- 2015 Sep;24(3):235-245.
- doi: 10.5607/en.2015.24.3.235
MTT assay is commonly used to assess the cellular cytotoxicity caused by anticancer drugs in glioblastomas. However, there have been some reports insisting that MTT assay exhibited non-specific intracellular reduction... -
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- Preliminary Study on Natural Killer Cell Activity for Interferon-Gamma Production after Gamma Knife Radiosurgery for Brain Tumors
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Park K, Jeong SS, Kim JH, Chung HT, Lee EJ, Moon HE, Park KH, Kim JW, Park HR, Lee JM, Lee HJ, Kim HR, Cho YH, Paek SH
- KMID: 2535847
- J Korean Neurosurg Soc.
- 2022 Nov;65(6):861-867.
- doi: 10.3340/jkns.2020.0339
Objective : High-dose radiation is well known to induce and modulate the immune system. This study was performed to evaluate the correlation between clinical outcomes and changes in natural killer... -
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- Mitochondrial Dysfunction in Parkinson's Disease
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Moon HE, Paek SH
- KMID: 2165544
- Exp Neurobiol.
- 2015 Jun;24(2):103-116.
- doi: 10.5607/en.2015.24.2.103
Parkinson's disease (PD) is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta (SNc) with motor and nonmotor symptoms. Defective mitochondrial function and increased oxidative... -
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- A Short Review on the Current Understanding of Autism Spectrum Disorders
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Park HR, Lee JM, Moon HE, Lee DS, Kim BN, Kim J, Kim DG, Paek SH
- KMID: 2165573
- Exp Neurobiol.
- 2016 Feb;25(1):1-13.
- doi: 10.5607/en.2016.25.1.1
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures... -
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- Inhibition of HIF1α and PDK Induces Cell Death of Glioblastoma Multiforme
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Han JE, Lim PW, Na CM, Choi YS, Lee JY, Kim Y, Park HW, Moon HE, Heo MS, Park HR, Kim DG, Paek SH
- KMID: 2398434
- Exp Neurobiol.
- 2017 Oct;26(5):295-306.
- doi: 10.5607/en.2017.26.5.295
Glioblastoma multiforme (GBM) is the most common and aggressive form of brain tumors. GBMs, like other tumors, rely relatively less on mitochondrial oxidative phosphorylation (OXPHOS) and utilize more aerobic glycolysis,... -
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- The Effect of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in a Collagenase-Induced Intracerebral Hemorrhage Rat Model
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Kim K, Park HW, Moon HE, Kim JW, Bae S, Chang JW, Oh W, Yang YS, Paek SH
- KMID: 2165549
- Exp Neurobiol.
- 2015 Jun;24(2):146-155.
- doi: 10.5607/en.2015.24.2.146
Intracerebral hemorrhage (ICH) is one of the devastating types of stroke. Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) have potential benefits in recovery from brain damage following ICH. This... -
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- Tumor Spheroids of an Aggressive Form of Central Neurocytoma Have Transit-Amplifying Progenitor Characteristics with Enhanced EGFR and Tumor Stem Cell Signaling
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Shin HY, Han KS, Park HW, Hong YH, Kim Y, Moon HE, Park KW, Park HR, Lee CJ, Lee K, Kim SJ, Heo MS, Park SH, Kim DG, Paek SH
- KMID: 2515812
- Exp Neurobiol.
- 2021 Apr;30(2):120-143.
- doi: 10.5607/en21004
Central neurocytoma (CN) has been known as a benign neuronal tumor. In rare cases, CN undergoes malignant transformation to glioblastomas (GBM). Here we examined its cellular origin by characterizing differentiation... -
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- Mitochondrial Dysfunction of Immortalized Human Adipose Tissue-Derived Mesenchymal Stromal Cells from Patients with Parkinson's Disease
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Moon HE, Yoon SH, Hur YS, Park HW, Ha JY, Kim KH, Shim JH, Yoo SH, Son JH, Paek SL, Kim IK, Hwang JH, Kim DG, Kim HJ, Jeon BS, Park SS, Paek SH
- KMID: 2284632
- Exp Neurobiol.
- 2013 Dec;22(4):283-300.
- doi: 10.5607/en.2013.22.4.283
Mitochondrial dysfunction in dopaminergic neurons of patients with idiopathic and familial Parkinson's disease (PD) is well known although the underlying mechanism is not clear. We established a homogeneous population of... -
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- High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients
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Cho SY, Park C, Na D, Han JY, Lee J, Park OK, Zhang C, Sung CO, Moon HE, Kim Y, Kim JH, Kim JJ, Khang SK, Nam DH, Choi JW, Suh YL, Kim DG, Park SH, Youn H, Yun K, Kim JI, Lee C, Paek SH, Park H
- KMID: 2382708
- Exp Mol Med.
- 2017 Apr;49(4):e317.
- doi: 10.1038/emm.2017.9
Gliosarcoma (GS) is a rare variant (2%) of glioblastoma (GBM) that poses clinical genomic challenges because of its poor prognosis and limited genomic information. To gain a comprehensive view of... -
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- COMP-Ang1 Potentiates EPC Treatment of Ischemic Brain Injury by Enhancing Angiogenesis Through Activating AKT-mTOR Pathway and Promoting Vascular Migration Through Activating Tie2-FAK Pathway
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Moon HE, Byun K, Park HW, Kim JH, Hur J, Park JS, Jun JK, Kim HS, Paek SL, Kim IK, Hwang JH, Kim JW, Kim DG, Sung YC, Koh GY, Song CW, Lee B, Paek SH
- KMID: 2052852
- Exp Neurobiol.
- 2015 Mar;24(1):55-70.
- doi: 10.5607/en.2015.24.1.55
Successful recovery from brain ischemia is limited due to poor vascularization surrounding the ischemic zone. Cell therapy with strong angiogenic factors could be an effective strategy to rescue the ischemic... -
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