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Prevalence of Laboratory Animal Allergy in Laboratory Workers

Son TJ, Bae JH, Rhee CS, Seong WK

  • KMID: 2312062
  • Lab Anim Res.
  • 2010 Jun;26(2):165-171.
This study was designed to analyze the prevalence rates of laboratory animal allergy (LAA) in laboratory workers who perform researches with animals, and detect the mouse urinary allergen (Mus m...
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ERRATUM: Comparing the Effects of Carvedilol Enantiomers on Regression of Established Cardiac Hypertrophy Induced by Pressure Overload

Hao J, Kim CH

  • KMID: 2312070
  • Lab Anim Res.
  • 2010 Jun;26(2):223-223.
No abstract available.
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Safety Evaluation of Human Fibroblasts in Mice: Tumorigenicity, 13-week Toxicity and Distribution Studies

Choi HJ, Kwon E, Sohn JH, Che JH, Lee KH, Kim JW, Choi J, Kang BC

  • KMID: 2312064
  • Lab Anim Res.
  • 2010 Jun;26(2):181-196.
Human fibroblasts were developed for cellular therapy with the aim of correcting of depressed scars, but the safety of that in vivo is unclear. In this study, we assessed the...
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Skin Whitening Effects of Sanguisorba officinalis and Stichopus japonicus

Lee MO, Oh HG, Park SH, Lee HA, Sul JD, Song J, Kim O

  • KMID: 2312057
  • Lab Anim Res.
  • 2010 Jun;26(2):127-132.
This study is aimed to evaluate skin whitening effects of Sanguisorba officinalis and Stichopus japonicus for cosmeceutical ingredients. The extract of Stichopus japonicus showed 61.78% inhibition of tyrosinase activity, and...
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Genetic Polymorphism of Jeju Horses by Microsatellite DNA Markers in Korea

Lee JE, Shin JH, Yun YM, Lee KK, Lee H, Kweon OK, Yun YS, Suh JG, Shin NS, Seong JK

  • KMID: 2312069
  • Lab Anim Res.
  • 2010 Jun;26(2):219-221.
We determined the genetic diversity and distance between Jeju and Thoroughbred horses by genotyping for 20 microsatellite loci consisting of (TG)n repetitive sequence. The expected heterozygosity ranged from 0.1 to...
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Reference Data of the Main Physiological Parameters in Control Sprague-Dawley Rats from Pre-clinical Toxicity Studies

Han ZZ, Xu HD, Kim KH, Ahn TH, Bae JS, Lee JY, Gil KH, Lee JY, Woo SJ, Yoo HJ, Lee HK, Kim KH, Park CK, Zhang HS, Song SW

  • KMID: 2312061
  • Lab Anim Res.
  • 2010 Jun;26(2):153-164.
The purpose of this paper is to provide reference data related to the body weight, food & water consumptions, urinalysis, hematology and serum biochemistry parameters and absolute & relative organ...
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Fractionation of DNases Specific to Haemonchus contortus Intestine by Phenyl Sepharose Column

Seo MG, Kim TH, Kwon OD, Jeong KS, Lee YJ, Kim SJ, Park SJ, Kwon YS, Kwak DM

  • KMID: 2312059
  • Lab Anim Res.
  • 2010 Jun;26(2):139-144.
Multiple DNases were identified from Haemonchus contortus intestine based on previous studies. The DNases detected at 34, 36 and 38.5 kDa had diverse characteristics. Some of them had characteristics similar...
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A Tumoral Calcinosis Case in a Beagle Dog

Shin SK, Kim G, Chang D, Na KJ, Ahn B

  • KMID: 2312068
  • Lab Anim Res.
  • 2010 Jun;26(2):215-218.
We describe a case of tumoral calcinosis in a 13-month-old female Beagle dog presenting for surgical removal of a 4x3x3 cm mass in the soft tissues of the medial right...
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Uterine Adenomyosis in Beagle Dogs

Kim HS, Kang SC, Zhang HS, Kang JS, Kim JH, Kim KH, Kang BH, Yoon BI

  • KMID: 2312067
  • Lab Anim Res.
  • 2010 Jun;26(2):211-213.
Adenomyosis is a nonneoplastic hyperplastic lesion, characterized by invagination of proliferating endometrial glands into myometrium. In dogs, uterine adenomyosis is relatively rare and it is important in Toxicologic Pathology to...
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The Effect of Quercetin on the BK(Ca) in Umbilical Cord Vein-derived Mesenchymal Stem Cells

Park KS, Kim Y

  • KMID: 2312066
  • Lab Anim Res.
  • 2010 Jun;26(2):203-209.
Recently, we demonstrated that a large conductance Ca2+-activated K+ channel (BK(Ca)) in human umbilical cord vein-derived mesenchymal cells (hUC-MSCs). In this study, we studied effects of quercetin, the flavonoid used...
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Bex1 Participates in Muscle Regeneration by Regulating Myogenic Satellite Cell Differentiation

Koo JH

  • KMID: 2312060
  • Lab Anim Res.
  • 2010 Jun;26(2):145-151.
Bex1 protein is upregulated in regenerating muscle and interacts with calmodulin, a Ca2+-binding protein involved in cell cycle regulation. Following cardiotoxin-induced injury the regenerating muscle of Bex1 knock-out mice exhibits...
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Expression Patterns of Superoxide Dismutase Genes in the Stage-specific Seminiferous Tubules of Mice Excised by a Laser Capture Microdissection

Yon JM, Jung AY, Park JH, Hong MK, Kim JS, Lin C, Kim MR, Baek IJ, Lee BJ, Yun YW, Nam SY

  • KMID: 2312065
  • Lab Anim Res.
  • 2010 Jun;26(2):197-201.
Spermatogenesis is a particularly difficult process to study the unique multiple cellular associations within the seminiferous epithelium. Laser capture microdissection (LCM) is a recently developed technique that enables the isolation...
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Aspectual Comparison of the Skin Changes in Hairless Mice According to the Aging Type

Choi KH, Kim YC, Kim BH

  • KMID: 2312063
  • Lab Anim Res.
  • 2010 Jun;26(2):173-180.
The purpose of this study was to compare the skin changes in female SKH-1 hairless mice between UVB irradiated photo-aged group and endogenous aged group. The UVB irradiation and endogenous...
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Determining NOEL/NOAEL in Repeated-dose Toxicity Studies, When the Low Dose Group Shows Significant Difference in Quantitative Data

Kobayashi , Pillai KS, Michael M, Cherian KM, Ohnishi M

  • KMID: 2312058
  • Lab Anim Res.
  • 2010 Jun;26(2):133-137.
In repeated-dose 28-day oral toxicity study design, the low dose is fixed as the no observed effect level (NOEL). But, in practice the low dose usually shows significant difference in...
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