- Regulation of Inflammation by Bidirectional Signaling through CD137 and Its Ligand
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Kwon B
- KMID: 2150746
- Immune Netw.
- 2012 Oct;12(5):176-180.
- doi: 10.4110/in.2012.12.5.176
Although the majority of research on CD137 has been directed to T cells, it is becoming clear that this molecule has distinct functions in other lineages of cells, including non-hematopoietic... -
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- Mucosal Immune System and M Cell-targeting Strategies for Oral Mucosal Vaccination
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Kim SH, Lee KY, Jang YS
- KMID: 2150745
- Immune Netw.
- 2012 Oct;12(5):165-175.
- doi: 10.4110/in.2012.12.5.165
Vaccination is one of the most effective methods available to prevent infectious diseases. Mucosa, which are exposed to heavy loads of commensal and pathogenic microorganisms, are one of the first... -
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- Rheumatoid Fibroblast-like Synoviocytes Downregulate Foxp3 Expression by Regulatory T Cells Via GITRL/GITR Interaction
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Kim SH, Youn J
- KMID: 2150752
- Immune Netw.
- 2012 Oct;12(5):217-221.
- doi: 10.4110/in.2012.12.5.217
Fibroblast-like synoviocytes (FLS) colocalize with leukocyte infiltrates in rheumatoid synovia. Proinflammatory leukocytes are known to amplify inflammation by signaling to FLS, but crosstalk between FLS and regulatory T cells (Tregs)... -
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- Polyacetylene Compound from Cirsium japonicum var. ussuriense Inhibited Caspase-1-mediated IL-1beta Expression
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Shim H, Moon JS, Lee S, Yim D, Kang TJ
- KMID: 2150751
- Immune Netw.
- 2012 Oct;12(5):213-216.
- doi: 10.4110/in.2012.12.5.213
Our previous report showed that polyacetylene compound, 1-Heptadecene-11, 13-diyne-8, 9, 10-triol (PA) from the root of Cirsium japonicum var. ussuriense has anti-inflammatory activity. In this study we investigated the role... -
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- Vitamin C Induces Apoptosis in Human Colon Cancer Cell Line, HCT-8 Via the Modulation of Calcium Influx in Endoplasmic Reticulum and the Dissociation of Bad from 14-3-3beta
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Kim JE, Kang JS, Lee WJ
- KMID: 2150748
- Immune Netw.
- 2012 Oct;12(5):189-195.
- doi: 10.4110/in.2012.12.5.189
It has been reported that vitamin C plays an effective role in the treatment and prevention of cancer, but its specific mechanisms are still largely unknown. The incidence of colon... -
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- Immunomodulatory Effects of Dioscoreae Rhizome Against Inflammation through Suppressed Production of Cytokines Via Inhibition of the NF-kappaB Pathway
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Kim S, Shin S, Hyun B, Kong H, Han S, Lee A, Lee S, Kim K
- KMID: 2150747
- Immune Netw.
- 2012 Oct;12(5):181-188.
- doi: 10.4110/in.2012.12.5.181
Dioscoreae Rhizome (DR) has been used in traditional medicine to treat numerous diseases and is reported to have anti-diabetes and anti-tumor activities. To identify a bioactive traditional medicine with anti-inflammatory... -
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- T Cell Immunoglobulin Mucin Domain (TIM)-3 Promoter Activity in a Human Mast Cell Line
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Kim JS, Shin DC, Woo MY, Kwon MH, Kim K, Park S
- KMID: 2150750
- Immune Netw.
- 2012 Oct;12(5):207-212.
- doi: 10.4110/in.2012.12.5.207
T cell immunoglobulin mucin domain (TIM)-3 is an immunomodulatory molecule and upregulated in T cells by several cytokines. TIM-3 also influences mast cell function but its transcriptional regulation in mast... -
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- Glutamine and Leucine Provide Enhanced Protective Immunity Against Mucosal Infection with Herpes Simplex Virus Type 1
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Uyangaa E, Lee HK, Eo SK
- KMID: 2150749
- Immune Netw.
- 2012 Oct;12(5):196-206.
- doi: 10.4110/in.2012.12.5.196
Besides their role as building blocks of protein, there are growing evidences that some amino acids have roles in regulating key metabolic pathways that are necessary for maintenance, growth, reproduction,... -
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