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Editor's Introduction to This Issue

Chung YJ

No abstract available.
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Ultra-rare Disease and Genomics-Driven Precision Medicine

Lee S, Choi M

Since next-generation sequencing (NGS) technique was adopted into clinical practices, revolutionary advances in diagnosing rare genetic diseases have been achieved through translating genomic medicine into precision or personalized management. Indeed,...
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Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters

Choi W, Lee J, Lee JY, Lee SM, Kim DW, Kim YJ

Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of...
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Multilevel Precision-Based Rational Design of Chemical Inhibitors Targeting the Hydrophobic Cleft of Toxoplasma gondii Apical Membrane Antigen 1 (AMA1)

Vetrivel U, Muralikumar S, Mahalakshmi B, Lily Therese K, Madhavan H, Alameen M, Thirumudi

Toxoplasma gondii is an intracellular Apicomplexan parasite and a causative agent of toxoplasmosis in human. It causes encephalitis, uveitis, chorioretinitis, and congenital infection. T. gondii invades the host cell by...
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Genome-Wide Association Study of Bone Mineral Density in Korean Men

Bae YS, Im SW, Kang MS, Kim JH, Lee SH, Cho BL, Park JH, Nam YS, Son HY, Yang SD, Sung J, Oh KH, Yun JM, Kim JI

Osteoporosis is a medical condition of global concern, with increasing incidence in both sexes. Bone mineral density (BMD), a highly heritable trait, has been proven a useful diagnostic factor in...
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