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Microarray Screening for Genes Involved in Oligodendrocyte Differentiation in the Zebrafish CNS

Chung AY, Kim S, Kim H, Bae YK, Park HC

Within the vertebrate nervous system, myelination is required for the normal function of neurons by facilitating the rapid conduction of action potentials along axons. Oligodendrocytes are glial cells which myelinate...
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Changes in the Histone Acetylation Patterns during the Development of the Nervous System

Cho B, Kim HJ, Kim H, Sun W

Epigenetic modification such as DNA methylation and histone acetylation plays essential roles in many aspects of cellular function and development of animals. There is an increasing amounts of evidence for...
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Simple and Novel Three Dimensional Neuronal Cell Culture Using a Micro Mesh Scaffold

Yoo SJ, Kim J, Lee CS, Nam Y

Conventional method of cell culture studies has been performed on two-dimensional substrates. Recently, three-dimensional (3D) cell culture platforms have been a subject of interest as cells in 3D has significant...
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The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders

Kang DE, Roh SE, Woo JA, Liu T, Bu JH, Jung AR, Lim Y

The major defining pathological hallmarks of Alzheimer's disease (AD) are the accumulations of Abeta in senile plaques and hyperphosphorylated tau in neurofibrillary tangles and neuropil threads. Recent studies indicate that...
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Interactions of Dopamine D1 and N-methyl-D-Aspartate Receptors are Required for Acute Cocaine-Evoked Nitric Oxide Efflux in the Dorsal Striatum

Lee DK, Ahn SM, Shim YB, Koh WC, Shim I, Choe ES

Alterations in nitric oxide (NO) release in response to psychostimulants in the striatum cause a plastic change contributing to the development and expression of addiction. In this study, regulation of...
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Alternations of Septal-hippocampal System in the Adult Wistar Rat with Spatial Memory Impairments Induced by Chronic Cerebral Hypoperfusion

Choi BR, Kwon KJ, Park SH, Jeon WK, Han SH, Kim HY, Han JS

In the current investigation, the status of the septo-hippocampal cholinergic pathway and hippocampal mitogen-activated protein kinase (MAPK) signaling was examined in male Wistar rats with chronic cerebral hypoperfusion, which showed...
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Protective Effect of Coriolus versicolor Cultivated in Citrus Extract Against Nitric Oxide-Induced Apoptosis in Human Neuroblastoma SK-N-MC Cells

Kim BC, Kim YS, Lee JW, Seo JH, Ji ES, Lee H, Park YI, Kim CJ

Nitric oxide (NO) is a reactive free radical and a messenger molecule in many physiological functions. However, excessive NO is believed to be a mediator of neurotoxicity. The medicinal plant...
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