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Nicotine Prevents MPTP-induced Dopaminergic Neurodegeneration

Kim JM, O JJ, Jeon BS

Epidemiological studies of Parkinson disease (PD) have found an inverse correlation between cigarette smoking and the risk of developing PD, which suggests that nicotine has a protective effect. Results from...
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Classification of BMI Control Commands Using Extreme Learning Machine from Spike Trains of Simultaneously Recorded 34 CA1 Single Neural Signals

Lee Y, Lee H, Lang Y, Kim J, Lee M, Shin HC

A recently developed machine learning algorithm referred to as Extreme Learning Machine (ELM) was used to classify machine control commands out of time series of spike trains of ensembles of...
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Behavioral Manifestation of Neuropathic Pain Following Sciatic Nerve Section in Rats

Yoo DJ, Na HS, Yoon YW

The present study was performed to observe the time course of behavioral signs of painful sensations in sciatic neurectomy animal model and to test the effects of sympathectomy and saphenous...
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Striatal CREB Phosphorylation Following Cued/Response Learning in the Water Maze Differ in Two Inbred Strains of Mice

Hwang YK, Han JS

Much evidence shows that the hippocampus and striatum play roles as important neural substrates for spatial/place and cued/response learning, respectively. This experiment was conducted to investigate the engagement of the...
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Protective Effect of Orally Administrated Dandelion Against Carrageenan-induced Ankle Arthritis in Rats

Sur BJ, Koh YJ, Choi HD, Shim I, Lee H, Hahm DH

Dandelion (DA) possesses the therapeutic ability to eliminate heat and alleviating swelling, choleresis, dieresis, and inflammation. In order to investigate the anti-arthritic effect of DA, several behavioral parameters such as...
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The Central and Peripheral Production of Pro-inflammatory Cytokine, IL-1b after Immune and Stress Stimulation in Rats

Jung EY, Kim KS, Shim I

Interleukin-1beta (IL-1beta), one of the pro-inflammatory cytokines, acts as an endogenous pyrogen and is an important mediator of behavioral and physiological responses to immune stimulation as well as exposure to...
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Protective Effect of Shenqi-wan on Traumatic Brain Injury-induced Delayed Apoptosis in Rat Hippocampal Dentate Gyrus

Kwon OB, Lim HH, Song YK, Lee JW, Kim YS, Kim CJ

Shenqi-wan, Oriental herbal medicine formulation, has been traditionally used for delayed mental and physical development in children, complications of diabetes, and glomerulonephritis. In the present study, the protective effect of...
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Modulation of Amygdalin on Glycine- and Glutamate-induced Ion Currents in Rat Periaqueductal Gray Neurons

Lee GJ, Lim HH, Song YK, Shin MC, Shin MS, Kim CJ

Amygdalin is known as vitamain B17, and it was called laetrile. Amygdalin is composed of two molecules of glucose, one molecule of benzaldehyde which induces an analgesic action, and one...
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Effects of Armeniacae Semen and Amygdalin on the Lipopolysaccaride-induced Prostaglandin E2 Synthesis and Nitric Oxide Production in Mouse BV2 Microglial Cells

Jung HJ, Kim YS, Shin MS, Kim CJ, Kim YS

Armeniacae semen has been used in traditional medicine for the treatment of pain and inflammatory diseases. Amygdalin is the major compound of Armeniacae semen, and it is used for treatment...
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