- Analysis of trimethylsilyl derivatization products of phosphatidylethanol by gas chromatography-mass spectrometry
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Yon CS, Han JS
- KMID: 755107
- Exp Mol Med.
- 2000 Dec;32(4):243-245.
For the detection of rare phospholipid, phosphatidylethanol (PEt), GC-MS analysis method was adopted for the detection of derivatization products of PEt by N,O-bis (trimethylsilyl) trifluroacetamide (BSTFA). A re-structured... -
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- Purification of clathrin assembly protein from rat liver
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Kim HL, Kim JA
- KMID: 755103
- Exp Mol Med.
- 2000 Dec;32(4):222-226.
Recently, the gene encoding clathrin assembly protein of lymphoid myeloid leukemia (CALM), which is homologous to the AP180, was cloned from rat brain, and its expression differential to... -
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- Characterization of an unusual variant mRNA of human lysosomal alpha-mannosidase
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Sun H, Wolfe JH
- KMID: 755097
- Exp Mol Med.
- 2000 Dec;32(4):187-192.
Lysosomal alpha-mannosidase (EC 3.2.1.24) is an exoglycosidase in the glycoprotein degradation pathway and is encoded by a 3.0 kb cDNA. A 2.3 kb cDNA from a minor species... -
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- Alternative splicing in 5'-untranslational region of STK-15 gene, encoding centrosome associated kinase, in breast cancer cell lines
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Shin SO, Lee KH, Kim JH, Baek SH, Park JW, Gabrielson EW, Kwon TK
- KMID: 755098
- Exp Mol Med.
- 2000 Dec;32(4):193-196.
Centrosomes maintain genomic stability by establishing the bipolar spindles during cell division and, execute accurate segregation of chromosomes during mitosis. In this study, we have demonstrated that there... -
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- Activation of JNK and p38 in rat hippocampus after kainic acid induced seizure
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Jeon SH, Kim YS, Bae CD, Park JB
- KMID: 755104
- Exp Mol Med.
- 2000 Dec;32(4):227-230.
Kainic acid, an analogue of glutamate, causes limbic seizures and induces cell death in the rat brain. We examined the activation of MAPK family kinases; ERKs, JNKs and... -
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- Y chromosome microdeletions in idiopathic azoospermia and non-mosaic type of Klinefelter syndrome
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Lee YH, Kim T, Kim MH, Kim YT, Kim SH
- KMID: 755105
- Exp Mol Med.
- 2000 Dec;32(4):231-234.
The objective of this study was to elucidate the cause of the spermatogenic defect in idiopathic azoospermia and non-mosaic type of Klinefelter syndrome. Genomic DNAs from 9 cases... -
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- Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity
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Kim HS, Jeong SY, Lee JH, Kim BE, Kim JW, Jeong SW, Kim IK
- KMID: 755099
- Exp Mol Med.
- 2000 Dec;32(4):197-203.
3-Deazaadenosine (DZA), one of the potent inhibitors of S-adenosylhomocysteine hydrolase, is known to possess several biological properties including an induction of apoptosis. To evaluate a possibility that DZA... -
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- Environments of ethidium binding to allosteric Dna: II. Accessibility, mobility and mode of binding
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Suh DC
- KMID: 755100
- Exp Mol Med.
- 2000 Dec;32(4):204-209.
DNA binding compounds were previously shown to bind to the right-handed DNA forms and hybrid B-Z forms in a highly cooperative manner and indicate that structural specificity plays... -
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- Multi-facet expressions of adenylate cyclase isoforms in B16-F10 melanoma cells differentiated by forskolin treatment
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Cho DH, Bae CD, Juhnn YS
- KMID: 755106
- Exp Mol Med.
- 2000 Dec;32(4):235-242.
The terminal differentiation of malignant melanoma cells is known to be induced by activating cAMP signaling pathway with alpha-MSH or cAMP analogues. However, sustained activation of cAMP signaling... -
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- Association of castration-dependent early induction of c-myc expression with a cell proliferation of the ventral prostate gland in rat
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Lim K, Park C, Kim YK, Yun KA, Son MY, Lee YC, Park JI, Lee JH, Sul CK, Lee CS, Park SK, Hwang BD
- KMID: 755102
- Exp Mol Med.
- 2000 Dec;32(4):216-221.
The protooncogene c-myc is known to be associated with both cell proliferation and apoptosis. The possible cellular affects of castration on the ventral prostate gland of rat as... -
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- Atrial natriuretic peptide induces rat peritoneal mast cell activation by cGMP-independent and calcium uptake-dependent mechanism
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Chai OH, Lee YH, Han EH, Kim HT, Lee MS, Song CH
- KMID: 755096
- Exp Mol Med.
- 2000 Dec;32(4):179-186.
Atrial natriuretic peptide (ANP), a 28 amino acid basic polypeptide, is known to induce histamine release from human and rat mast cells in vitro and cause a wheel... -
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- Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells
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Kim KM, Lee KH, Hong YS, Park HY
- KMID: 755108
- Exp Mol Med.
- 2000 Dec;32(4):246-254.
Fas transduces apoptotic signals upon cross-linking with the Fas ligand (FasL), which is experimentally replaced by agonistic anti-Fas monoclonal antibodies (mAb). Of eight human malignant hematopoietic cell lines... -
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- Varying expression levels of colony stimulating factor receptors in disease states and different leukocytes
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Lee KY, Suh BG, Kim JW, Lee WB, Kim SY, Kim YY, Lee JH, Lim JH, Lim MS, Kang CS, Han KJ
- KMID: 755101
- Exp Mol Med.
- 2000 Dec;32(4):210-215.
Administration of G-CSF may not always respond in rise of neutrophil counts in different patient population. In order to understand a possible inter-relationship between the G-CSF and GM-CSF... -
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