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Family of Li-Fraumeni Syndrome with a Germline Mutation in the p53 Gene

Shin HJ, Kwon YJ, Lim YJ, Park BK, Ghim TT, Shin SH, Kong SY, Hong EK, Park HJ

  • KMID: 2168956
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):38-42.
Li-Fraumeni syndrome is an autosomal dominant familial cancer syndrome characterized by a diverse set of tumors, including sarcoma, breast cancer, brain tumor, adrenocortical carcinoma, and acute leukemia, affecting family members....
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Role of Cyclosporine A in Pediatric Patients with Refractory Chronic Idiopathic Thrombocytopenic Purpura

Kim MJ, Kim HS, Kwon SY, Won SC, Kim BS, Choi SY, Lyu CJ

  • KMID: 2168951
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):1-8.
PURPOSE: Since the treatment of chronic idiopathic thrombocytopenic purpura (ITP) remains unsatisfactory in patients refractory to standard therapy, alternative therapies such as splenectomy, danazol, rituximab and cyclosporine A (CsA) are...
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A Case of Cystic Partially Differentiated Nephroblastoma

Baek DW, Kim HS, Kwon SY, Kim BS, Choi SY, Cho NH, Won SC, Lyu CJ

  • KMID: 2168954
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):27-31.
Cystic partially differentiated nephroblastoma is a rare renal mass in children. Since its clinical characteristics and radiologic findings are very similar to those of cystic Wilms tumor and cystic...
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Effective Management of Kaposiform Hemangioendotheliomas Associatedwith Kasabach-Merritt Syndrome Using Chemotherapy

Kim MJ, Jin JH, Lee JE, Cheong WS, Choi GS, Kim JM, Kim SK

  • KMID: 2168959
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):54-58.
Although Kaposiform hemangioendothelioma (KHE) is a rare benign tumor, it is well known for its aggressiveness, showing mortality rates as high as 24% when progressed to Kasabach- Meritt syndrome....
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A Case of Autologous Cord Blood Stem Cell Transplantationin Stage IV Neuroblastoma

Chae JH, Kim HS, Kwon SY, Won SC, Kim BS, Choi SY, Lyu CJ

  • KMID: 2168953
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):21-26.
Since High dose chemotherapy (HDCT) with autologous hematopoietic stem cell (HSC) rescue has been reported to be the most effective current treatment modality in advanced and refractory neuroblastoma, various types...
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A Case of Hemophagocytic Syndrome Induced by Adenovirus Infection after Splenectomy

Park SH, Lee KS

  • KMID: 2168958
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):49-53.
Hemophagocytic lymphohistiocytosis (HLH) is a rare but sometimes fatal disease. Its main features are prolonged fever, hepatosplenomegaly, cytopenias, and hemophagocytosis in the bone marrow, lymph nodes and other tissues. Hemophagocytic...
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Langerhans Cell Histiocytosis in a Two-month-old Infant

Baek JM, Sohn SY, Yang JH, Woo CW, Kim YS, Kim IH, Lee J, Lee K

  • KMID: 2168955
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):32-37.
Langerhans cell histiocytosis (LCH) is a rare condition characterized by the proliferation of distinctive histiocytes. The clinical manifestations and outcomes of LCH vary from a skin-only self-healing condition to...
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Thiamine Deficiency Manifested by Wernicke's Encephalopathy and Wet Beriberi in a Patient with Rhabdomyosarcoma Following Chemotherapy and Total Parenteral Nutrition

Joo JW, Baek HJ, Han DK, Yang EM, Chung TW, Kook H, Hwang TJ

  • KMID: 2168957
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):43-48.
Beriberi and Wernicke's encephalopathy (WE) are potentially lethal, serious diseases caused by thiamine deficiency. The most common cause is malnutrition associated with chronic alcoholism, but it may occur in...
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Clinical Characteristics and Treatment Outcome of Infantile Acute Lymphoblastic Leukemia

Cho HJ, Han DK, Baek HJ, Park EY, Lee SJ, Kook H, Hwang TJ

  • KMID: 2168952
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):9-20.
PURPOSE: Acute lymphoblastic leukemia (ALL) in infancy accounts for about 2~4% cases of childhood ALL and is biologically different from that of older children with an extremely poor prognosis. The...
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