Healthc Inform Res.  2024 Jan;30(1):42-48. 10.4258/hir.2024.30.1.42.

Deep Learning Model and its Application for the Diagnosis of Exudative Pharyngitis

Affiliations
  • 1Department of Paediatrics, National University of Singapore, Singapore
  • 2Department of Cardiology, National Heart Centre, Singapore
  • 3NUS High School of Math and Science, Singapore
  • 4Department of Diagnostic Radiology, Singapore General Hospital, Singapore

Abstract


Objectives
Telemedicine is firmly established in the healthcare landscape of many countries. Acute respiratory infections are the most common reason for telemedicine consultations. A throat examination is important for diagnosing bacterial pharyngitis, but this is challenging for doctors during a telemedicine consultation. A solution could be for patients to upload images of their throat to a web application. This study aimed to develop a deep learning model for the automated diagnosis of exudative pharyngitis. Thereafter, the model will be deployed online.
Methods
We used 343 throat images (139 with exudative pharyngitis and 204 without pharyngitis) in the study. ImageDataGenerator was used to augment the training data. The convolutional neural network models of MobileNetV3, ResNet50, and EfficientNetB0 were implemented to train the dataset, with hyperparameter tuning.
Results
All three models were trained successfully; with successive epochs, the loss and training loss decreased, and accuracy and training accuracy increased. The EfficientNetB0 model achieved the highest accuracy (95.5%), compared to MobileNetV3 (82.1%) and ResNet50 (88.1%). The EfficientNetB0 model also achieved high precision (1.00), recall (0.89) and F1-score (0.94).
Conclusions
We trained a deep learning model based on EfficientNetB0 that can diagnose exudative pharyngitis. Our model was able to achieve the highest accuracy, at 95.5%, out of all previous studies that used machine learning for the diagnosis of exudative pharyngitis. We have deployed the model on a web application that can be used to augment the doctor’s diagnosis of exudative pharyngitis.

Keyword

Artificial Intelligence, Deep Learning, Diagnosis, Pharyngitis, Telemedicine

Figure

  • Figure 1 (A) A normal pharynx. (B) A diseased pharynx with exudative pharyngitis, as can be seen by the white exudates on the tonsils. Some of the exudates have been circled for clearer illustration.

  • Figure 2 The methodology used in this paper for the automated diagnosis of exudative pharyngitis.

  • Figure 3 The training results for three models: (A) training loss, (B) training accuracy, (C) loss, and (D) accuracy. For all three models, the training loss decreased, and the training accuracy increased with successive epochs of training. The loss decreased and the accuracy increased with training.

  • Figure 4 Receiver operating characteristic (ROC) curve for the EfficientNetB0 model. The area under the ROC curve was 0.975.

  • Figure 5 Confusion matrix for the EfficientNetB0 model. The EfficientNetB0 model achieved high precision (1.00), recall (0.89), and F1-score (0.94).

  • Figure 6 Screenshot of our web application for users (doctors or patients) to upload throat images for the automated diagnosis of exudative pharyngitis.

  • Figure 7 Screenshot of our web application that displays the correct diagnosis after a user has uploaded an image of his throat. In this case, the patient requires antibiotics to prevent complications such as rheumatic fever and rheumatic heart disease.


Reference

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