Oral Biol Res.  2021 Dec;45(4):237-247. 10.21851/obr.45.04.202112.237.

Sinus floor augmentation using a mineralized freeze-dried bone graft combined with recombinant human bone morphogenetic protein-2: clinical and histological results of three cases

Affiliations
  • 1Resident, Department of Periodontology, School of Dentistry, Chosun University, Gwangju, Republic of Korea
  • 2Assistant Professor, Department of Periodontology, School of Dentistry, Chosun University, Gwangju, Republic of Korea
  • 3Professor, Department of Periodontology, School of Dentistry, Chosun University, Gwangju, Republic of Korea

Abstract

The purpose of this study was to evaluate clinical and histological outcomes using a freeze-dried bone allograft (FDBA) combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) in sinus floor augmentation. Sinus floor augmentation was performed in three patients using the FDBA and rhBMP-2. After a 5-month healing period, biopsies were performed simultaneously with implant surgery. It was possible to obtain enough bone to place implants quantitatively and to obtain excellent initial fixation of implants qualitatively. In this case series, the results showed that rhBMP-2 encourages bone formation and enough bone can be made to place implants when performing sinus floor augmentation with FDBA.

Keyword

Allograft; Bone morphogenetic protein 2; Sinus floor augmentation
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